CRISPR Citations

OriGene产品已被全世界的科学家广泛使用，以提高他们的研究效率。 为了供您参考，我们收集了一些使用OriGene产品发表过的代表性的引用文献，将其发布在此页面上。

使用基因名称或靶标名称搜索文献

这是研究人员使用OriGene产品后最新发表的一些论文。

靶点 研究论文 杂志 产品类型 货号
Virosecurinine induces apoptosis in human leukemia THP-1 cells and other underlying molecular mechanisms Oncology Letters CRISPR GE100007
An Efficient Targeted Mutagenesis System Using CRISPR/Cas in Monocotyledons Current Protocols in Plant Biology CRISPR GE100007
An Efficient Targeted Mutagenesis System Using CRISPR/Cas in Monocotyledons. Current protocols in plant biology CRISPR GE100007
ABCB5 Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5 Int. J. Cancer CRISPR KN415604
Activin A Receptor Type IB Loss of ACVRIB leads to increased squamous cell carcinoma aggressiveness through alterations in cell-cell and cell-matrix adhesion proteins Am J Cancer Res CRISPR KN206920
ADAM8 Degradome of soluble ADAM10 and ADAM17 metalloproteases Cell. Mol. Life Sci. CRISPR KN213386
AIM Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L. Nature communications CRISPR KN406528
AP2M1 Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target Sci. Adv. CRISPR KN401377
APC APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway Dev. Cell CRISPR KN211629
Argonaute 2 RNA interference may suppress stress granule formation by preventing argonaute 2 recruitment American Journal of Physiology - Cell Physiology CRISPR KN218078
beta Arrestin 1 In vitro impact of FSH glycosylation variants on FSH receptor-stimulated signal transduction and functional selectivity Journal of the Endocrine Society CRISPR KN201279
Beta Arrestin 2 In vitro impact of FSH glycosylation variants on FSH receptor-stimulated signal transduction and functional selectivity Journal of the Endocrine Society CRISPR KN201168
C1D Ovotransferrin Exhibits Osteogenic Activity Partially via Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Activation in MC3T3-E1 Cells J. Agric. Food Chem. CRISPR KN502339
c20orf72 Replication fork rescue in mammalian mitochondria Sci Rep CRISPR KN203886
CA12 P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors Oncotarget CRISPR KN204034
CA150 Role for the splicing factor TCERG1 in Cajal body integrity and snRNP assembly. Journal of cell science CRISPR KN217192
Caspase 10 Endothelial p130cas confers resistance to anti-angiogenesis therapy Cell reports CRISPR KN206379
Caspase 10 Endothelial p130cas Confers Resistance to Anti-Angiogenesis Therapy Conference CRISPR KN206379
CCN1 Cyr61/CCN1 regulates dCK and CTGF and Causes Gemcitabine Resistant Phenotype in Pancreatic Ductal Adenocarcinoma Mol. Cancer Ther. CRISPR KN203492
CCR5 CCL5-CCR5 interactions modulate metabolic events during tumor onset to promote tumorigenesis BMC Cancer CRISPR KN216008
CD28 Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation. Nature cancer CRISPR KN411318
CD28 Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation Nat Cancer CRISPR KN211318
CED6 GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma Sci Signal CRISPR KN221580
CRISPR The Krüppel-like factor 9 cistrome in mouse hippocampal neurons reveals predominant transcriptional repression via proximal promoter binding BMC Genomics CRISPR GE100018
CRISPR MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload Cell Rep CRISPR GE100025
CRISPR Product Genome editing in rice and wheat using the CRISPR/Cas system Nat Protoc CRISPR GE100007
CRISPR vector YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression Nucleic Acids Res., May 2016; 10.1093/nar/gkw418. CRISPR GE100002
CRISPR Vector G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits J. Cell Biol., Mar 2016; 212: 845 - 860. CRISPR GE100001
CRISPR Vector Hypertension Causing Mutations in Cullin3 Impair RhoA Ubiquitination and Augment Association with Substrate Adaptors J. Biol. Chem. CRISPR GE100018
CRISPR Vector Regulation of vascular function: roles for Cullin-3 and RhoBTB1 In Ppar?-mediated blood pressure control Thesis CRISPR GE100018
CSDE1 Cold Shock Domain Containing E1 (CSDE1) Protein is Overexpressed and can be Targeted to Inhibit Invasiveness in Pancreatic Cancer Cells Proteomics CRISPR KN207101
CTNND1 P120 catenin potentiates constitutive E-cadherin dimerization at the plasma membrane and regulates trans binding Current biology : CB CRISPR KN422771
CTSB Cathepsin B inhibition blocks neurite outgrowth in cultured neurons by regulating lysosomal trafficking and remodeling J. Neurochem. CRISPR KN303984
Cyclophilin A Coronaviruses and arteriviruses display striking differences in their cyclophilin A-dependence during replication in cell culture Virology CRISPR KN203307
Cytochrome P450 1A2 Transglutaminase 4 as a prostate autoantigen in male subfertility. Science translational medicine CRISPR KN421636
delta 2 Catenin Frequently rearranged and overexpressed δ-catenin is responsible for low sensitivity of prostate cancer cells to androgen receptor and β-catenin antagonists Oncotarget CRISPR KN224464
DPH2 Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing Sci Rep CRISPR KN201382
DROSHA DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis Cells CRISPR KN304817
EGFR Prognostic Value of EGFR Expression for Patients With Stage III Colorectal Cancer Receiving Fluoropyrimidine Metronomic Maintenance Therapy After Radical Resection and Adjuvant Oxaliplatin-Based Chemotherapy Oncology Research CRISPR KN214877
EGFR Prognostic Value of EGFR Expression for Patients with Stage III Colorectal Cancer Receiving Fluoropyrimidine Metronomic Maintenance Therapy After Radical Resection and Adjuvant Oxaliplatin-Based Chemotherapy Oncol. Res. CRISPR KN414877
FOXA2 Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer Am J Physiol Gastrointest Liver Physiol. CRISPR KN204066
FRS2 Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression J. Biol. Chem. CRISPR KN306139
GBA GBA Regulates EMT/MET and Chemoresistance in Squamous Cell Carcinoma Cells by Modulating the Cellular Glycosphingolipid Profile Cells CRISPR KN201614BN
GCN2 Activation of Gcn2 by small molecules designed to be inhibitors The Journal of Biological Chemistry CRISPR KN412459
GCN2 GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis eLife CRISPR KN412459
GPD2 Metformin targets Mitochondrial Glycerophosphate Dehydrogenase (mGPDH) to control Rate of Oxidative Phosphorylation and growth of thyroid cancer in vitro and in vivo Clin. Cancer Res. CRISPR KN213341
GRB2 Regulation of microRNA expression by the adaptor protein GRB2 Scientific Reports CRISPR KN200469
Grp75 GRP75 as a functional element of cholix transcytosis Tissue Barriers CRISPR KN201397
Hexokinase II Multi-Functional MPT Protein as a Therapeutic Agent against Mycobacterium tuberculosis Biomedicines CRISPR KN209482
HHAT Hedgehog Acyltransferase Promotes Uptake of Palmitoyl-CoA across the Endoplasmic Reticulum Membrane Cell Rep CRISPR KN208447
HTT Huntingtin protein maintains balanced energetics in mouse cardiomyocytes Nucleosides Nucleotides Nucleic Acids CRISPR KN308042
HTT ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington\'s disease: a novel approach for cell clock research Mol. Psychiatry CRISPR KN308042
Ido1 Dual inhibition of IDO1/TDO2 enhances anti-tumor immunity in platinum-resistant non-small cell lung cancer. Cancer & metabolism CRISPR KN508091
IFITM1 Disrupting interferon-alpha and NF-kappaB crosstalk suppresses IFITM1 expression attenuating triple-negative breast cancer progression Cancer letters CRISPR KN201617
IL1 beta Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5 Int. J. Cancer CRISPR KN402079
IL6 Targeting Interleukin-6 (IL-6) Sensitizes Anti-PD-L1 Treatment in a Colorectal Cancer Preclinical Model Med. Sci. Monit. CRISPR KN308293
IL8 Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5 Int. J. Cancer CRISPR KN202075
ITIH5 Inter-α-Trypsin Inhibitor Heavy Chain 5 (ITIH5) Is a Natural Stabilizer of Hyaluronan That Modulates Biological Processes in the Skin Skin Pharmacol Physiol CRISPR KN214478
KIF26B Genome-wide association and functional analyses identify CASC20 and KIF26B as target loci in heterotopic ossification BioRxiv CRISPR KN308785
MAMDC4 The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation Cell Mol Gastroenterol Hepatol CRISPR KN216843
MEK5 The WNK1-ERK5 route plays a pathophysiological role in ovarian cancer and limits therapeutic efficacy of trametinib. Clinical and translational medicine CRISPR KN203171
MOV10 Effect of P-body component Mov10 on HCV virus production and infectivity FASEB J. CRISPR KN400934
mtTFA Mitochondrial DNA Copy Number (mtDNA-CN) Can Influence Mortality and Cardiovascular Disease via Methylation of Nuclear DNA CpGs bioRxiv CRISPR KN215488
NANS Generation of an NANS homozygous knockout human induced pluripotent stem cell line by the insertion of GFP-P2A-Puro via CRISPR/Cas9 editing. Stem cell research CRISPR KN400123
NAT1 Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex Int. J. Biochem. Cell Biol. CRISPR KN221042
NAT1 Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability PLoS ONE CRISPR KN221042
Negative Control 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors Molecular brain CRISPR GE100003
NEO1 Netrin-1 functions as a suppressor of bone morphogenetic protein (BMP) signaling Scientific reports CRISPR KN310902RB
NTN1 Netrin-1 functions as a suppressor of bone morphogenetic protein (BMP) signaling Scientific reports CRISPR KN511288
OGT O-GlcNAc modification of Sox2 regulates self-renewal in pancreatic cancer by promoting its stability Theranostics CRISPR KN206822
OGT O-GlcNAc modification of oncogenic transcription factor Sox2 promotes protein stability and regulates self-renewal in pancreatic cancer bioRxiv CRISPR KN206822
ORAI1 Genetic Manipulation of Calcium Release-Activated Calcium Channel 1 Modulates the Multipotency of Human Cartilage-Derived Mesenchymal Stem Cells Journal of Immunology Research CRISPR KN210034
OVCA1 Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing Sci Rep CRISPR KN221955
P Glycoprotein Carbonic anhydrase XII inhibitors overcome P-glycoprotein-mediated resistance to temozolomide in glioblastoma Mol. Cancer Ther. CRISPR KN216080
p53 Histone deacetylase inhibitor quisinostat activates caspase signaling and upregulates p53 acetylation to inhibit the proliferation of HepG2 cells. Molecular medicine reports CRISPR KN200003
p53 mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis Int J Mol Sci CRISPR KN200003
pAAVS1-Puro-DNR Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to Oesophageal Adenocarcinoma bioRxiv CRISPR GE100024
Parathyroid Hormone Receptor 1 Novel bone-targeted parathyroid hormone-related peptide antagonists inhibit breast cancer bone metastases Anti-cancer drugs CRISPR KN412841
Parkin The ubiquitin E3 ligase Parkin regulates neuronal Ca V 1.3 channel functional expression. Journal of neurophysiology CRISPR KN216186
pCas-Guide Proteomic Analysis of eIF5B Silencing-Modulated Proteostasis PLoS ONE CRISPR GE100002
pCas-Guide Cloning Mesenchymal Stem Cell Engineering Methods Mol. Biol. CRISPR GE100001
pCas-Guide Cloning Kit L1 retrotransposon antisense RNA within ASAR lncRNAs controls chromosome-wide replication timing J. Cell Biol. CRISPR GE100001
pCas-Guide-EF1a-GFP CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair Sci Adv CRISPR GE100018
pCas-Guide-GFP Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature Cancer Cell CRISPR GE100018
pCAS-Scramble Loss of USF2 promotes proliferation, migration and mitophagy in a redox-dependent manner Redox Biol CRISPR GE100003
pCas-Scramble TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation Nat Commun CRISPR GE100003
pCAS-Scramble A Safe Harbor-Targeted CRISPR/Cas9 Homology Independent Targeted Integration (HITI) System for Multi-Modality Reporter Gene-Based Cell Tracking bioRxiv CRISPR GE100003
pCAS-Scramble MAFG-driven astrocytes promote CNS inflammation Nature CRISPR GE100003
pCas-Scramble Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection Nat Commun CRISPR GE100003
pCAS-Scramble Collagen IV (COL4A1, COL4A2), a Component of the Viral Biofilm, Is Induced by the HTLV-1 Oncoprotein Tax and Impacts Virus Transmission Front Microbiol CRISPR GE100003
PGP Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death Cells CRISPR KN414470
PLAUR The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres Sci Rep CRISPR KN201222
pLenti-Cas-Guide Impact of fatty acid binding protein 5-deficiency on COPD exacerbations and cigarette smoke-induced inflammatory response to bacterial infection Clin Transl Med CRISPR GE100010
PML Protein PML plays both inimical and beneficial roles in HSV-1 replication Proc. Natl. Acad. Sci. U.S.A. CRISPR KN200700
PPAR gamma Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L. Nature communications CRISPR KN401538
PRNP Changes in cellular prion protein expression, Processing and localization during differentiation of the neuronal cell line CAD 5 Biol. Cell CRISPR KN313942
PTEN BRCA1-Associated Protein-1 Suppresses Osteosarcoma Cell Proliferation and Migration Through Regulation PI3K/Akt Pathway DNA Cell Biol CRISPR KN202627
PTGES The COX2 effector microsomal PGE2 synthase-1 is a regulator of immunosuppression in cutaneous melanoma Clin. Cancer Res. CRISPR KN314172
PTGS2 Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment Front Pharmacol CRISPR KN314183
RECQL5 RECQL5 KIX domain splicing isoforms have distinct functions in transcription repression and DNA damage response DNA Repair CRISPR KN409460
REST Histone deacetylase inhibitors induce medulloblastoma cell death independent of HDACs recruited in REST repression complexes Mol Genet Genomic Med CRISPR KN514675
RHOB The critical role of dysregulated RhoB signaling pathway in radioresistance of colorectal cancer Int. J. Radiat. Oncol. Biol. Phys. CRISPR KN209837
RTL3 A retrotransposon gag-like-3 gene RTL3 and SOX-9 co-regulate the expression of COL2A1 in chondrocytes Connect Tissue Res CRISPR KN519666
SA2 A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers Nat Commun CRISPR KN400261
SCNM1 Mutations in SCNM1 cause orofaciodigital syndrome due to minor intron splicing defects affecting primary cilia. American journal of human genetics CRISPR KN400987
Sigma1 receptor Development of a Novel σ 1 Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells. ACS chemical neuroscience CRISPR KN201206
SLC20A2 Vitamin-D receptor agonist calcitriol reduces calcification in vitro through selective upregulation of SLC20A2 but not SLC20A1 or XPR1 Sci Rep CRISPR KN206029
SLC25A22 In Colorectal Cancer Cells With Mutant KRAS, SLC25A22-Mediated Glutaminolysis Reduces DNA Demethylation to Increase WNT Signaling, Stemness, and Drug Resistance Gastroenterology CRISPR KN203650
SMURF 2 SMURF2 prevents detrimental changes to chromatin, protecting human dermal fibroblasts from chromosomal instability and tumorigenesis Oncogene CRISPR KN210866
SMURF 2 Generation of SMURF2 knockout human cells using the CRISPR/Cas9 system Anal. Biochem. CRISPR KN210866
SOX4 SOX4 activates CXCL12 in hepatocellular carcinoma cells to modulate endothelial cell migration and angiogenesis in vivo Oncogene CRISPR KN209139
SPARC Albumin-binding photosensitizer capable of targeting glioma via the SPARC pathway Biomaterials Research CRISPR KN409964
SPTSSA SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia Brain CRISPR KN409747
STAT3 Autologous reconstitution of human cancer and immune system in vivo Oncotarget CRISPR KN204922
STAT3 Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3 Cell Commun. Signal CRISPR KN316845
TIFA Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis PLoS Pathog. CRISPR KN204357
TIMP2 TIMP2 facilitates CIRI through activating NLRP3-mediated pyroptosis Aging (Albany NY) CRISPR KN209796
TNFRSF10B Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma Nat Commun CRISPR KN517973
TRPM2 Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates its Key Role in Cell Survival through Modulation of Mitochondrial ROS and Bioenergetics J. Biol. Chem. CRISPR KN216220
TXNDC TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux J. Cell Biol. CRISPR KN206187
UNC5B Repulsive Guidance Molecule a Inhibits Angiogenesis by Downregulating VEGF and Phosphorylated Focal Adhesion Kinase In Vitro Front Neurol CRISPR KN218267
VEGFA Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake Commun Biol CRISPR KN217312
Xbp1 Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides Cell Reports CRISPR KN519483
XBP1 XBP1 increases transactivation of somatic mutants of ESR1 and loss of XBP1 reverses endocrine resistance conferred by gain-of-function Y537S ESR1 mutation Heliyon CRISPR KN201959
ZCCHC8 ZCCHC8 is required for the degradation of pervasive transcripts originating from multiple genomic regulatory features bioRxiv CRISPR KN519669