Iws1 (BC068184) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR208664L4V

  • LentiORF®

Lenti ORF particles, Iws1 (GFP-tagged) - Mouse IWS1 homolog (S. cerevisiae) (cDNA clone MGC:93016 IMAGE:30639737), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 11115.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Iws1 (BC068184) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 1700069O15Rik; 3000008H23; AL117927; AW214353
Vector pLenti-C-mGFP-P2A-Puro
ACCN BC068184
ORF Size 1629 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR208664).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq BC068184, AAH68184
RefSeq Size 4353 bp
RefSeq ORF 1631 bp
Locus ID 73473
Gene Summary Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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