Iws1 (BC068184) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR208664L3V
- LentiORF®
-
Lenti ORF particles, Iws1 (Myc-DDK-tagged) - Mouse IWS1 homolog (S. cerevisiae) (cDNA clone MGC:93016 IMAGE:30639737), 200ul, >10^7 TU/mL
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CNY 9975.00
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Specifications
| Product Data | |
| Product Name | Iws1 (BC068184) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1700069O15Rik; 3000008H23; AL117927; AW214353 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC068184 |
| ORF Size | 1629 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR208664).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC068184, AAH68184 |
| RefSeq Size | 4353 bp |
| RefSeq ORF | 1631 bp |
| Locus ID | 73473 |
| Gene Summary | Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription (By similarity).[UniProtKB/Swiss-Prot Function] |
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