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SH3BP2 (NM_003023) Human Untagged Clone
CAT＃: SC128156
SH3BP2 (untagged)-Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1
CNY 6,272.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 3BP-2; 3BP2; CRBM; CRPM; RES4-23 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128156 sequence for NM_003023 edited (data generated by NextGen Sequencing)
ATGGCGGCTGAAGAGATGCATTGGCCTGTCCCTATGAAGGCCATTGGTGCCCAGAACCTG CTAACCATGCCTGGGGGCGTGGCCAAGGCTGGCTACCTGCACAAGAAGGGCGGTACCCAG CTGCAGCTGCTGAAATGGCCCCTGCGCTTTGTCATCATCCACAAACGCTGCGTCTACTAC TTCAAGAGTAGCACCTCTGCCTCCCCGCAGGGCGCCTTCTCCCTGAGTGGCTATAACCGG GTGATGCGGGCGGCTGAGGAGACCACGTCCAACAACGTTTTCCCCTTCAAGATCATCCAC ATCAGCAAGAAGCACCGCACGTGGTTCTTCTCGGCCTCCTCCGAGGAGGAGCGCAAGAGC TGGATGGCCTTGCTGCGCAGGGAGATTGGCCACTTCCACGAAAAGAAAGACCTGCCCTTG GACACCAGCGACTCCAGCTCGGACACAGACAGCTTCTACGGCGCAGTTGAGCGGCCTGTG GATATCAGCCTTTCCCCGTACCCCACGGACAATGAAGACTATGAGCACGACGATGAGGAT GACTCCTACCTGGAGCCTGACTCCCCGGAGCCCGGAAGGCTTGAGGATGCCCTGATGCAC CCACCGGCTTACCCACCACCCCCAGTGCCCACGCCCAGGAAGCCAGCCTTCTCTGACATG CCCCGGGCCCACTCCTTTACCTCCAAGGGCCCCGGTCCCCTACTGCCACCCCCGCCCCCT AAGCACGGCCTCCCAGATGTTGGCCTGGCTGCTGAGGACTCCAAGAGGGACCCACTGTGC CCGAGGCGGGCTGAGCCTTGCCCCAGGGTACCTGCTACCCCCCGAAGGATGAGCGATCCC CCTCTGAGCACCATGCCCACCGCACCCGGCCTCCGGAAACCCCCTTGCTTCCGGGAGAGT GCCAGCCCCAGCCCGGAGCCCTGGACCCCTGGCCACGGGGCCTGCTCCACTTCCAGTGCT GCCATCATGGCCACTGCCACCTCCAGAAACTGTGACAAACTCAAGTCCTTCCACCTGTCC CCCCGAGGACCACCCACATCTGAGCCCCCACCTGTGCCAGCCAACAAGCCCAAGTTCCTG AAGATAGCTGAAGAGGACCCCCCAAGGGAGGCAGCCATGCCCGGACTCTTTGTGCCCCCC GTGGCTCCCCGGCCTCCTGCGCTGAAGCTGCCAGTGCCTGAGGCCATGGCGCGGCCCGCA GTCCTGCCCAGGCCAGAGAAGCCGCAGCTCCCGCACCTCCAGCGATCACCCCCCGATGGG CAGAGTTTCAGGAGCTTCTCCTTTGAAAAGCCCCGGCAACCCTCACAGGCTGACACTGGC GGGGACGACTCGGACGAGGACTATGAGAAGGTGCCACTGCCCAACTCGGTCTTCGTCAAC ACCACGGAGTCCTGCGAAGTGGAAAGGTTGTTCAAGGCTACAAGCCCCCGGGGAGAGCCC CAGGATGGACTCTACTGCATCCGGAACTCCTCTACCAAGTCGGGGAAGGTCCTGGTTGTG TGGGACGAAACCTCTAACAAAGTGAGGAACTATCGCATTTTTGAGAAGGACTCTAAGTTC TACCTGGAGGGCGAGGTCCTGTTTGTGAGTGTGGGCAGCATGGTGGAGCACTACCACACC CACGTGCTGCCCAGCCACCAGAGCCTGCTGCTGCGGCACCCCTACGGCTACACTGGGCCT AGGTGA Clone variation with respect to NM_003023.4 300 t=>c >OriGene 5' read for NM_003023 unedited
GGGAGTCGGATTTGTATACGACTCATATAGGCGGCCGCGNATTCAGATCTGGTACCGGTC CGGAATTCCCGGGATATCGTCGACCCACGCGTCCGGCGGGCGGGACGGAGCTGCGGCGGC GGCGGGTCCCGCGGGCGGGAGCGCCTGGCGGCCGAGTCAAGCCGCCGCCTCGACCCAGGG CCCGCGGGCCAGGAGAGCGCTCGGCGGCTTCATGGCGGCTGAAGAGATGCATTGGCCTGT CCCTATGAAGGCCATTGGTGCCCAGAACCTGCTAACCATGCCTGGGGGCGTGGCCAAGGC TGGCTACCTGCACAAGAAGGGCGGTACCCAGCTGCAGCTGCTGAAATGGCCCCTGCGCTT TGTCATCATCCACAAACGCTGCGTCTACTACTTCAAGAGTAGCACCTCTGCCTCCCCGCA GGGCGCCTTCTCCCTGAGTGGCTATAACCGGGTGATGCGGGCGGCTGAGGAGACCACGTC CAACAACGTTTTCCCCTTCAAGATCATCCACATCAGCAAGAAGCACCGCACGTGGTTCTT CTCGGCCTCCTCCGAGGAGGAGCGCAAGAGCTGGATGGCCTTGCTGCGCAGGGAGATTGG CCACTTCCACGAAAAGAAAGACCTGCCCTTGGACACCAGCGACTCCAGCTCGGACACAGA CAGCTTCTACGGCGCAGTTGAGCGGCCTGTGGATATCAGCCTTTTCCCGTACCCCACGGN ACATGAAGACTATGAGCACGACGATGAGGATGACTCCTACCTGGAGCCTGACTCCCCGGA GCCCGGAAGGGCTGAGATGCCCTGATGCACCCACCGGCTTACCCACCACCCCCAGTGCCC ACGCCCAGGAAGCCAGCCTTCTCTGACATGGCCCGGGCCCACTCCTTTACCTC |
| Restriction Sites | Please inquire |
| ACCN | NM_003023 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003023.2, NP_003014.2 |
| RefSeq Size | 7300 bp |
| RefSeq ORF | 1686 bp |
| Locus ID | 6452 |
| UniProt ID | P78314 |
| Domains | SH2, PH |
| Protein Families | Druggable Genome |
| Protein Pathways | Natural killer cell mediated cytotoxicity |
| Gene Summary | The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] Transcript Variant: This variant (1) represents use of an alternative promoter and 5' UTR and uses a downstream translation start site, compared to variant 3. The resulting isoform (a) has a shorter N-terminus, compared to isoform b. Both variants 1 and 2 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205759 | SH3BP2 (Myc-DDK-tagged)-Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1 |
CNY 6,264.00 |
|
| RC205759L1 | Lenti ORF clone of Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1, Myc-DDK-tagged |
CNY 8,664.00 |
|
| RC205759L2 | Lenti ORF clone of Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1, mGFP tagged |
CNY 8,664.00 |
|
| RC205759L3 | Lenti ORF clone of Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC205759L4 | Lenti ORF clone of Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1, mGFP tagged |
CNY 6,460.00 |
|
| RG205759 | SH3BP2 (tGFP-tagged) - Human SH3-domain binding protein 2 (SH3BP2), transcript variant 1 |
CNY 7,864.00 |
