CD70 Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) CD70（Gln39-Pro193）+hFc（Glu99-Ala330）+6×His
Tag	C-Human Fc and 6×His
Predicted MW	44.1 kDa
Purity	> 95%
Buffer	Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Preparation	Affinity purification
Storage	Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing.
Stability	12 months from date of despatch
Reference Data
Locus ID	970
UniProt ID	P32970
Summary	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Protein Families	ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction

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