DR5 (TNFRSF10B) Human Recombinant Protein
CNY 4925.00
Product images
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence |
TNFRSF10B （Ile56-Glu186）+mFc（Pro99-Lys330）
|
| Tag | C-Mouse Fc |
| Predicted MW | 40.5 kDa |
| Purity | > 95% |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Preparation | Affinity purification |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Reference Data | |
| Locus ID | 8795 |
| UniProt ID | O14763 |
| Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity, p53 signaling pathway |
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Resources
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC401260 | TNFRSF10B HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC407781 | TNFRSF10B HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY401260 | Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1 |
CNY 3080.00 |
|
| LY407781 | Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2 |
CNY 3080.00 |
|
| PH319808 | TNFRSF10B MS Standard C13 and N15-labeled recombinant protein (NP_671716) |
CNY 19520.00 |
|
| TP319808 | Recombinant protein of human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, 20 µg |
CNY 2900.00 |
|
| TP720636 | Purified recombinant protein of Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1 |
CNY 1800.00 |
