DR5 (TNFRSF10B) (NM_003842) Human Recombinant Protein
CAT＃: TP720636
Purified recombinant protein of Human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1
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CNY 1800.00
| Cited in 1 publication. |
Product images
CNY 1999.00
CNY 2700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence |
Ile56-Glu182
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| Tag | C-His |
| Predicted MW | 15.19 kDa |
| Concentration | lot specific |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
| Reference Data | |
| RefSeq | NP_003833 |
| Locus ID | 8795 |
| UniProt ID | O14763 |
| Refseq Size | 4154 |
| Cytogenetics | 8p21.3 |
| Refseq ORF | 1320 |
| Synonyms | CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9 |
| Summary | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009] |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity, p53 signaling pathway |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
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Acid/bile exposure triggers TRAIL-mediated apoptosis in esophageal cancer cells by suppressing the decoy receptors and c-FLIPR.
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The international journal of biochemistry cell biology
,PubMed ID 32135301
[TNFRSF10B]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC401260 | TNFRSF10B HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
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| LC407781 | TNFRSF10B HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
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| LY401260 | Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 1 |
CNY 3080.00 |
|
| LY407781 | Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2 |
CNY 3080.00 |
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| PH319808 | TNFRSF10B MS Standard C13 and N15-labeled recombinant protein (NP_671716) |
CNY 19520.00 |
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| TP319808 | Recombinant protein of human tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, 20 µg |
CNY 2900.00 |
|
| TP724002 | Human TNFRSF10B Protein, mFc Tag |
CNY 4925.00 |
