MATK (NM_139355) Human Recombinant Protein
CAT#: TP323161
Recombinant protein of human megakaryocyte-associated tyrosine kinase (MATK), transcript variant 1, 20 µg
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC223161 representing NM_139355
Red=Cloning site Green=Tags(s) MAGRGSLVSWRAFHGCDSAEELPRVSPRFLRAWHPPPVSARMPTRRWAPGTQCITKCEHTRPKPGELAFR KGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHGKISGQEAVQQLQPPE DGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVFFCNLMDMVEHYSKDKGAICTKLVRP KRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVM TKMQHENLVRLLGVILHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVH RDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSY GRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELRSAGAPAS VSGQDADGSTSPRSQEP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 56.3 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_647612 |
| Locus ID | 4145 |
| UniProt ID | P42679 |
| Refseq Size | 2183 |
| Cytogenetics | 19p13.3 |
| Refseq ORF | 1521 |
| Synonyms | CHK; CTK; HHYLTK; HYL; HYLTK; Lsk |
| Summary | The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome, Protein Kinase, Stem cell - Pluripotency |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC408299 | MATK HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC408300 | MATK HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
|
| LC419363 | MATK HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
|
| LY408299 | Transient overexpression lysate of megakaryocyte-associated tyrosine kinase (MATK), transcript variant 3 |
CNY 3080.00 |
|
| LY408300 | Transient overexpression lysate of megakaryocyte-associated tyrosine kinase (MATK), transcript variant 1 |
CNY 4840.00 |
|
| LY419363 | Transient overexpression lysate of megakaryocyte-associated tyrosine kinase (MATK), transcript variant 2 |
CNY 4840.00 |
|
| PH300454 | MATK MS Standard C13 and N15-labeled recombinant protein (NP_647611) |
CNY 19520.00 |
|
| PH323161 | MATK MS Standard C13 and N15-labeled recombinant protein (NP_647612) |
CNY 19520.00 |
|
| TP300454 | Recombinant protein of human megakaryocyte-associated tyrosine kinase (MATK), transcript variant 3, 20 µg |
CNY 2900.00 |
