PACRG (NM_001080378) Human Recombinant Protein
CAT＃: TP322240
Recombinant protein of human PARK2 co-regulated (PACRG), transcript variant 2, 20 µg
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CNY 2900.00
CNY 6650.00
| Cited in 1 publication. |
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CNY 600.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC222240 protein sequence
Red=Cloning site Green=Tags(s) MVAEKETLSLNKCPDKMPKRTKLLAQQPLPVHQPHSLVSEGFTVKAMMKNSVVRGPPAAGAFKERPTKPT AFRKFYERGDFPIALEHDSKGNKIAWKVEIEKLDYHHYLPLFFDGLCEMTFPYEFFARQGIHDMLEHGGN KILPVLPQLIIPIKNALNLRNRQVICVTLKVLQHLVVSAEMVGKALVPYYRQILPVLNIFKNMNVNSGDG IDYSQQKRENIGDLIQETLEAFERYGGENAFINIKYVVPTYESCLLN TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 29.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Bioactivity | In vitro ubiquitination assay (PMID: 28038320) |
| Reference Data | |
| RefSeq | NP_001073847 |
| Locus ID | 135138 |
| UniProt ID | Q96M98 |
| Refseq Size | 1585 |
| Cytogenetics | 6q26 |
| Refseq ORF | 771 |
| Synonyms | GLUP; HAK005771; PACRG2.1; PARK2CRG |
| Summary | This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
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Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis
,Gong, Y;Schumacher, SE;Wu, WH;Tang, F;Beroukhim, R;Chan, TA;,
Neoplasia
,PubMed ID 28038320
[PACRG]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC407578 | PACRG HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
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| LC421606 | PACRG HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC421607 | PACRG HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY407578 | Transient overexpression lysate of PARK2 co-regulated (PACRG), transcript variant 1 |
CNY 3080.00 |
|
| LY421606 | Transient overexpression lysate of PARK2 co-regulated (PACRG), transcript variant 2 |
CNY 3080.00 |
|
| LY421607 | Transient overexpression lysate of PARK2 co-regulated (PACRG), transcript variant 3 |
CNY 3080.00 |
|
| PH322240 | PACRG MS Standard C13 and N15-labeled recombinant protein (NP_001073847) |
CNY 19520.00 |
