MECR (NM_016011) Human Mass Spec Standard

Specifications

Product Data
Description	MECR MS Standard C13 and N15-labeled recombinant protein (NP_057095)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC224634
Predicted MW	40.4 kDa
Protein Sequence	Sequence Link (showhide) >RC224634 protein sequence Red=Cloning site Green=Tags(s) MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVELKNLELAAVRG SDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRT EAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLR TINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGG TMVTYGGMAKQPVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPL QDYQSALEASMKPFISSKQILTM TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057095
RefSeq Size	2539
RefSeq ORF	1119
Synonyms	CGI-63; DYTOABG; ETR1; FASN2B; NRBF1
Locus ID	51102
Cytogenetics	1p35.3
Summary	The protein encoded by this gene is an oxidoreductase that catalyzes the last step in mitochondrial fatty acid synthesis. Defects in this gene are a cause of childhood-onset dystonia and optic atrophy. [provided by RefSeq, Mar 2017]
Protein Families	Druggable Genome
Protein Pathways	Fatty acid elongation in mitochondria, Metabolic pathways

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