HEPACAM (NM_152722) Human Mass Spec Standard

Specifications

Product Data
Description	HEPACAM MS Standard C13 and N15-labeled recombinant protein (NP_689935)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC223693
Predicted MW	46 kDa
Protein Sequence	Sequence Link (showhide) >Peptide sequence encoded by RC223693 Blue=ORF Red=Cloning site Green=Tag(s) MKRERGALSRASRALRLAPFVYLLLIQTDPLEGVNITSPVRLIHGTVGKSALLSVQYSSTSSDRPVVKW QLKRDKPVTVVQSIGTEVIGTLRPDYRDRIRLFENGSLLLSDLQLADEGTYEVEISITDDTFTGEKTIN LTVDVPISRPQVLVASTTVLELSEAFTLNCSHENGTKPSYTWLKDGKPLLNDSRMLLSPDQKVLTITRV LMEDDDLYSCMVENPISQGRSLPVKITVYRRSSLYIILSTGGIFLLVTLVTVCACWKPSKRKQKKLEKQ NSLEYMDQNDDRLKPEADTLPRSGEQERKNPMALYILKDKDSPETEENPAPEPRSATEPGPPGYSVSPA VPGRSPGLPIRSARRYPRSPARSPATGRTHSSPPRAPSSPGRSRSASRTLRTAGVHIIREQDEAGPVEI SA TRTRPLEQKLISEEDLAANDILDYKDDDDKV Recombinant protein using RC223693 also available, TP323693
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_689935
RefSeq Size	3258
RefSeq ORF	1248
Synonyms	GlialCAM; HEPN1; MLC2A; MLC2B
Locus ID	220296
Cytogenetics	11q24.2
Summary	The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene. [provided by RefSeq, Jul 2011]
Protein Families	Druggable Genome, Transmembrane

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