TrkC (NTRK3) (NM_001012338) Human Mass Spec Standard

CAT#: PH319113

NTRK3 MS Standard C13 and N15-labeled recombinant protein (NP_001012338)



  View other "TrkC" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Anti-NTRK3 (TrkC) mouse monoclonal antibody, clone OTI2B8 (formerly 2B8)
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Specifications

Product Data
Description NTRK3 MS Standard C13 and N15-labeled recombinant protein (NP_001012338)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219113
Predicted MW 94.43 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001012338
RefSeq Size 2860
RefSeq ORF 2517
Synonyms gp145(trkC); GP145-TrkC; TRKC
Locus ID 4916
Cytogenetics 15q25.3
Summary This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Neurotrophin signaling pathway
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