PDE6 gamma (PDE6G) (NM_002602) Human Mass Spec Standard

Specifications

Product Data
Description	PDE6G MS Standard C13 and N15-labeled recombinant protein (NP_002593)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC216236
Predicted MW	9.6 kDa
Protein Sequence	Sequence Link (showhide) >RC216236 protein sequence Red=Cloning site Green=Tags(s) MNLEPPKAEFRSATRVAGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPW EAFNHLELHELAQYGII TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002593
RefSeq Size	1064
RefSeq ORF	261
Synonyms	PDEG; RP57
Locus ID	5148
Cytogenetics	17q25.3
Summary	This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]
Protein Families	Druggable Genome
Protein Pathways	Progesterone-mediated oocyte maturation, Purine metabolism

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