FKBP11 (NM_016594) Human Mass Spec Standard

Specifications

Product Data
Description	FKBP11 MS Standard C13 and N15-labeled recombinant protein (NP_057678)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206481
Predicted MW	22.2 kDa
Protein Sequence	Sequence Link (showhide) >RC206481 protein sequence Red=Cloning site Green=Tags(s) MTLRPSLLPLHLLLLLLLSAAVCRAEAGLETESPVRTLQVETLVEPPEPCAEPAAFGDTLHIHYTGSLVD GRIIDTSLTRDPLVIELGQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVEL IALIRANYWLKLVKGILPLVGMAMVPALLGLIGYHLYRKANRPKVSKKKLKEEKRNKSKKK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057678
RefSeq Size	767
RefSeq ORF	603
Synonyms	FKBP19
Locus ID	51303
Cytogenetics	12q13.12
Summary	FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).[supplied by OMIM, Mar 2008]
Protein Families	Druggable Genome, Transmembrane

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