REG1 beta (REG1B) (NM_006507) Human Mass Spec Standard

Specifications

Product Data
Description	REG1B MS Standard C13 and N15-labeled recombinant protein (NP_006498)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206451
Predicted MW	18.7 kDa
Protein Sequence	Sequence Link (showhide) >RC206451 protein sequence Red=Cloning site Green=Tags(s) MAQTNSFFMLISSLMFLSLSQGQESQTELPNPRISCPEGTNAYRSYCYYFNEDPETWVDADLYCQNMNSG NLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDPKKNRRWHWSSGSLVSYKSWDTGSPSSANAGYCASL TSCSGFKKWKDESCEKKFSFVCKFKN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006498
RefSeq Size	812
RefSeq ORF	498
Synonyms	PSPS2; REGH; REGI-BETA; REGL
Locus ID	5968
Cytogenetics	2p12
Summary	This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]

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