IDI2 (NM_033261) Human Mass Spec Standard

Specifications

Product Data
Description	IDI2 MS Standard C13 and N15-labeled recombinant protein (NP_150286)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204632
Predicted MW	26.8 kDa
Protein Sequence	Sequence Link (showhide) >RC204632 protein sequence Red=Cloning site Green=Tags(s) MSDINLDWVDRRQLQRLEEMLIVVDENDKVIGADTKRNCHLNENIEKGLLHRAFSVVLFNTKNRILIQQR SDTKVTFPGYFTDSCSSHPLYNPAELEEKDAIGVRRAAQRRLQAELGIPGEQISPEDIVFMTIYHHKAKS DRIWGEHEICYLLLVRKNVTLNPDPSETKSILYLSQEELWELLEREARGEVKVTPWLRTIAERFLYRWWP HLDDVTPFVELHKIHRV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_150286
RefSeq Size	1359
RefSeq ORF	681
Synonyms	IPPI2
Locus ID	91734
Cytogenetics	10p15.3
Summary	The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2016]
Protein Pathways	Metabolic pathways, Terpenoid backbone biosynthesis

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