RTKN (NM_033046) Human Mass Spec Standard

CAT#: PH304517

RTKN MS Standard C13 and N15-labeled recombinant protein (NP_149035)



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CNY 19520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description RTKN MS Standard C13 and N15-labeled recombinant protein (NP_149035)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204517
Predicted MW 61.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_149035
RefSeq Size 2638
RefSeq ORF 1650
Locus ID 6242
Cytogenetics 2p13.1
Summary This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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