TBC1D5 (NM_014744) Human Mass Spec Standard
CAT＃: PH304401
TBC1D5 MS Standard C13 and N15-labeled recombinant protein (NP_055559)
View other "TBC1D5" proteins (7)
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CNY 19520.00
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Specifications
| Product Data | |
| Description | TBC1D5 MS Standard C13 and N15-labeled recombinant protein (NP_055559) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC204401 |
| Predicted MW | 89 kDa |
| Protein Sequence |
>RC204401 protein sequence
Red=Cloning site Green=Tags(s) MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWEELFVNNNYLA TIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIKEIHITNPRKVVGQQDLMINN PLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELL APIVFVLHCDHQAFLHASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLM TPIPFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLV VWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRP VTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSS SSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSPSVESLPGGREFTGSPPSSAT KKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVILQENLE KEDQILVSLAGLKQIKDILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQAS SETPGCTDRGNSDDFILISKDDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASS SNPSSSPDDDSSKDSGFTIVSPLDI TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_055559 |
| RefSeq Size | 7869 |
| RefSeq ORF | 2385 |
| Locus ID | 9779 |
| Cytogenetics | 3p24.3 |
| Summary | May act as a GTPase-activating protein (GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol; at least retromer displacement seems to require its catalytic activity (PubMed:19531583, PubMed:20923837). Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN); the function seems to require its catalytic activity. Involved in regulation of autophagy (PubMed:22354992). May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy induction. Involved in the trafficking of ATG9A upon activation of autophagy. May regulate the recruitment of ATG9A-AP2-containing vesicles to autophagic membranes (PubMed:24603492).[UniProtKB/Swiss-Prot Function] |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC415062 | TBC1D5 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC427408 | TBC1D5 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1470.00 |
|
| LY415062 | Transient overexpression lysate of TBC1 domain family, member 5 (TBC1D5), transcript variant 2 |
CNY 3080.00 |
|
| LY427408 | Transient overexpression lysate of TBC1 domain family, member 5 (TBC1D5), transcript variant 3 |
CNY 4840.00 |
|
| PH326171 | TBC1D5 MS Standard C13 and N15-labeled recombinant protein (NP_001127852) |
CNY 19520.00 |
|
| TP304401 | Recombinant protein of human TBC1 domain family, member 5 (TBC1D5), transcript variant 2, 20 µg |
CNY 2900.00 |
|
| TP326171 | Recombinant protein of human TBC1 domain family, member 5 (TBC1D5), transcript variant 3, 20 µg |
CNY 2900.00 |
