HSD17B14 (NM_016246) Human Mass Spec Standard

Specifications

Product Data
Description	HSD17B14 MS Standard C13 and N15-labeled recombinant protein (NP_057330)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202531
Predicted MW	28.3 kDa
Protein Sequence	Sequence Link (showhide) >RC202531 protein sequence Red=Cloning site Green=Tags(s) MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVK TLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINIS SLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGM LAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGCKASRSTPVDAPDIPS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057330
RefSeq Size	1277
RefSeq ORF	810
Synonyms	DHRS10; retSDR3; SDR47C1
Locus ID	51171
Cytogenetics	19q13.33
Summary	17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]
Protein Families	Druggable Genome

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