ProSAAS (PCSK1N) (NM_013271) Human Mass Spec Standard

Specifications

Product Data
Description	PCSK1N MS Standard C13 and N15-labeled recombinant protein (NP_037403)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201065
Predicted MW	27.37 kDa
Protein Sequence	Sequence Link (showhide) >RC201065 representing NM_013271 Red=Cloning site Green=Tags(s) MAGSPLLWGPRAGGVGLLVLLLLGLFRPPPALCARPVKEPRGLSAASPPLAETGAPRRFRRSVPRGEAAG AVQELARALAHLLEAERQERARAEAQEAEDQQARVLAQLLRVWGAPRNSDPALGLDDDPDAPAAQLARAL LRARLDPAALAAQLVPAPVPAAALRPRPPVYDDGPAGPDAEEAGDETPDVDPELLRYLLGRILAGSADSE GVAAPRRLRRAADHDVGSELPPEGVLGALLRVKRLETPAPQVPARRLLPP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_037403
RefSeq Size	990
RefSeq ORF	780
Synonyms	BigLEN; PEN; PROSAAS; SAAS; SCG8; SgVIII
Locus ID	27344
Cytogenetics	Xp11.23
Summary	The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. The proprotein is further processed into multiple short peptides. A polymorphism within this gene may be associated with obesity. [provided by RefSeq, Aug 2013]
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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