MIS12 (NM_024039) Human Mass Spec Standard

Specifications

Product Data
Description	MIS12 MS Standard C13 and N15-labeled recombinant protein (NP_076944)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200789
Predicted MW	24.1 kDa
Protein Sequence	Sequence Link (showhide) >RC200789 protein sequence Red=Cloning site Green=Tags(s) MSVDPMTYEAQFFGFTPQTCMLRIYIAFQDYLFEVMQAVEQVILKKLDGIPDCDISPVQIRKCTEKFLCF MKGHFDNLFSKMEQLFLQLILRIPSNILLPEDKCKETPYSEEDFQHLQKEIEQLQEKYKTELCTKQALLA ELEEQKIVQAKLKQTLTFFDELHNVGRDHGTSDFRESLVSLVQNSRKLQNIRDNVEKESKRLKIS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_076944
RefSeq Size	2543
RefSeq ORF	615
Synonyms	2510025F08Rik; hMis12; KNTC2AP; MTW1
Locus ID	79003
Cytogenetics	17p13.2
Summary	Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (PubMed:12515822, PubMed:15502821, PubMed:16585270). Essential for proper kinetochore microtubule attachments (PubMed:23891108).[UniProtKB/Swiss-Prot Function]

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