HSF1 Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	HSF1
Locus ID	3297
Kit Components	KN200314G1, HSF1 gRNA vector 1 in pCas-Guide CRISPR vector KN200314G2, HSF1 gRNA vector 2 in pCas-Guide CRISPR vector KN200314BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Reference Data
RefSeq	NM_005526
Synonyms	HSTF1
Summary	The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phosphorylation, which promotes binding by heat shock protein 90. [provided by RefSeq, Jul 2017]

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