Mouse Dmbx1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dmbx1
Locus ID	140477
Kit Components	GA212502G1, Dmbx1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212502G2, Dmbx1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212502G3, Dmbx1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025567, NM_130865
Synonyms	Atx; Cdmx; Mbx; Otx3
Summary	Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development, neonatal survival, postnatal growth, and nursing ability.[UniProtKB/Swiss-Prot Function]

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