Human Zinc transporter 8 (SLC30A8) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLC30A8
Locus ID	169026
Kit Components	GA116181G1, Zinc transporter 8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116181G2, Zinc transporter 8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116181G3, Zinc transporter 8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001172811, NM_001172813, NM_001172814, NM_001172815, NM_173851
Synonyms	ZnT-8; ZNT8
Summary	The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

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