Human KLB activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KLB
Locus ID	152831
Kit Components	GA115846G1, KLB gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115846G2, KLB gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115846G3, KLB gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175737
Synonyms	BKL
Summary	Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).[UniProtKB/Swiss-Prot Function]

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