Human FGD5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FGD5
Locus ID	152273
Kit Components	GA115830G1, FGD5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115830G2, FGD5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115830G3, FGD5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001320276, NM_152536
Synonyms	ZFYVE23
Summary	Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.[UniProtKB/Swiss-Prot Function]

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