Human SRD5A3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SRD5A3
Locus ID	79644
Kit Components	GA112513G1, SRD5A3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112513G2, SRD5A3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112513G3, SRD5A3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_024592
Synonyms	CDG1P; CDG1Q; KRIZI; SRD5A2L; SRD5A2L1
Summary	The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]

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