Human GGCT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GGCT
Locus ID	79017
Kit Components	GA112312G1, GGCT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112312G2, GGCT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112312G3, GGCT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199815, NM_001199816, NM_001199817, NM_024051, NR_037669
Synonyms	C7orf24; CRF21; GCTG; GGC
Summary	The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

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