GGCT Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Specificity	Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat Homology: Cow: 92%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Rabbit: 86%; Rat: 93%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	21kDa
Gene Name	gamma-glutamylcyclotransferase
Database Link	NP_076956 Entrez Gene 79017 Human UniProt ID O75223
Background	The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms	C7orf24; CRF21; FLJ11717; gamma-glutamylcyclotransferase; GCTG; Ggc; MGC3077
Reference Data
Protein Pathways	Glutathione metabolism

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