Human ACCN4 (ASIC4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ASIC4
Locus ID	55515
Kit Components	GA110772G1, ACCN4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110772G2, ACCN4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110772G3, ACCN4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018674, NM_182847
Synonyms	ACCN4; BNAC4
Summary	This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]

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