Human Syntrophin gamma 2 (SNTG2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SNTG2
Locus ID	54221
Kit Components	GA110078G1, Syntrophin gamma 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110078G2, Syntrophin gamma 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110078G3, Syntrophin gamma 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018968
Synonyms	G2SYN; SYN5
Summary	This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described. [provided by RefSeq, Jul 2008]

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