Human Inversin (INVS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	INVS
Locus ID	27130
Kit Components	GA109026G1, Inversin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA109026G2, Inversin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA109026G3, Inversin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001318381, NM_001318382, NM_014425, NM_183245, NR_051962, NR_134606
Synonyms	INV; NPH2; NPHP2
Summary	This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2012]

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