Inversin (INVS) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the C terminal region of human INVS
Specificity	Expected reactivity: Human Homology: Cow: 100%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%; Zebrafish: 86%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	117 kDa
Gene Name	inversin
Database Link	NP_055240 Entrez Gene 27130 Human UniProt ID Q9Y283
Background	This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms	INV; inversin; KIAA0573; MGC133080; MGC133081; Nephrocystin-2; NPH2; NPHP2
Reference Data

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