Human Phospholipase C beta 1 (PLCB1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLCB1
Locus ID	23236
Kit Components	GA108150G1, Phospholipase C beta 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108150G2, Phospholipase C beta 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108150G3, Phospholipase C beta 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_015192, NM_182734
Synonyms	EIEE12; PI-PLC; PLC-154; PLC-I; PLC154; PLCB1A; PLCB1B
Summary	The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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