Human VLDL Receptor (VLDLR) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	VLDLR
Locus ID	7436
Kit Components	GA105126G1, VLDL Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105126G2, VLDL Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105126G3, VLDL Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001018056, NM_003383, NM_001322225, NM_001322226
Synonyms	CAMRQ1; CARMQ1; CHRMQ1; VLDLRCH
Summary	The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009]

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