Human GSK3 beta (GSK3B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GSK3B
Locus ID	2932
Kit Components	GA101983G1, GSK3 beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101983G2, GSK3 beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101983G3, GSK3 beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001146156, NM_002093, NM_001354596
Synonyms	glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta; GSK3beta isoform
Summary	The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]

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