Human Calpain 1 (CAPN1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CAPN1
Locus ID	823
Kit Components	GA100576G1, Calpain 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100576G2, Calpain 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100576G3, Calpain 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001198868, NM_001198869, NM_001198870, NM_005186, NR_040008
Synonyms	CANP; CANP1; CANPL1; muCANP; muCL; SPG76
Summary	The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

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