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Kdm6a (NM_009483) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211981L3V
- LentiORF®
-
Lenti ORF particles, Kdm6a (Myc-DDK-tagged) - Mouse 4lysine (K)-specific demethylase 6A (Kdm6a), 200ul, >10^7 TU/mL
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CNY 20,045.00
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Specifications
| Product Data | |
| Product Name | Kdm6a (NM_009483) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Utx |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_009483 |
| ORF Size | 4272 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211981).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009483.1 |
| RefSeq Size | 5309 bp |
| RefSeq ORF | 4275 bp |
| Locus ID | 22289 |
| Gene Summary | Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (By similarity). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression (PubMed:21095589).[UniProtKB/Swiss-Prot Function] |
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