Rnf185 (BC014812) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR201843L4V
- LentiORF®
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Lenti ORF particles, Rnf185 (GFP-tagged) - Mouse ring finger protein 185 (cDNA clone MGC:19394 IMAGE:3153870), 200ul, >10^7 TU/mL
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CNY 7505.00
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Specifications
| Product Data | |
| Product Name | Rnf185 (BC014812) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | MGC19394 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | BC014812 |
| ORF Size | 576 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR201843).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC014812, AAH14812 |
| RefSeq Size | 2736 bp |
| RefSeq ORF | 578 bp |
| Locus ID | 193670 |
| Gene Summary | E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1. Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2 (By similarity).[UniProtKB/Swiss-Prot Function] |
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