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UBA2 (NM_005499) Human Untagged Clone
CAT＃: SC319458
UBA2 (untagged)-Human ubiquitin-like modifier activating enzyme 2 (UBA2)
CNY 2,950.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARX; HRIHFB2115; SAE2 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_005499.2
CTCGGTTCTCCCGCCTCCGCCTCCGCCGCGGCTCGTGGTTGTCCCGCCATGGCACTGTCG
CGGGGGCTGCCCCGGGAGCTGGCTGAGGCGGTGGCCGGGGGCCGGGTGCTGGTGGTGGGG GCGGGCGGCATCGGCTGCGAGCTCCTCAAGAATCTCGTGCTCACCGGTTTCTCCCACATC GACCTGATTGATCTGGATACTATTGATGTAAGCAACCTCAACAGACAGTTTTTGTTTCAA AAGAAACATGTTGGAAGATCAAAGGCACAGGTTGCCAAGGAAAGTGTACTGCAGTTTTAC CCGAAAGCTAATATCGTTGCCTACCATGACAGCATCATGAACCCTGACTATAATGTGGAA TTTTTCCGACAGTTTATACTGGTTATGAATGCTTTAGATAACAGAGCTGCCCGAAACCAT GTTAATAGAATGTGCCTGGCAGCTGATGTTCCTCTTATTGAAAGTGGAACAGCTGGGTAT CTTGGACAAGTAACTACTATCAAAAAGGGTGTGACCGAGTGTTATGAGTGTCATCCTAAG CCGACCCAGAGAACCTTTCCTGGCTGTACAATTCGTAACACACCTTCAGAACCTATACAT TGCATCGTTTGGGCAAAGTACTTGTTCAACCAGTTGTTTGGGGAAGAAGATGCTGATCAA GAAGTATCTCCTGACAGAGCTGACCCTGAAGCTGCCTGGGAACCAACGGAAGCCGAAGCC AGAGCTAGAGCATCTAATGAAGATGGTGACATTAAACGTATTTCTACTAAGGAATGGGCT AAATCAACTGGATATGATCCAGTTAAACTTTTTACCAAGCTTTTTAAAGATGACATCAGG TATCTGTTGACAATGGACAAACTATGGCGGAAAAGGAAACCTCCAGTTCCGTTGGACTGG GCTGAAGTACAAAGTCAAGGAGAAGAAACGAATGCATCAGATCAACAGAATGAACCCCAG TTAGGCCTGAAAGACCAGCAGGTTCTAGATGTAAAGAGCTATGCACGTCTTTTTTCAAAG AGCATCGAGACTTTGAGAGTTCATTTAGCAGAAAAGGGGGATGGAGCTGAGCTCATATGG GATAAGGATGACCCATCTGCAATGGATTTTGTCACCTCTGCTGCAAACCTCAGGATGCAT ATTTTCAGTATGAATATGAAGAGTAGATTTGATATCAAATCAATGGCAGGGAACATTATT CCTGCTATTGCTACTACTAATGCAGTAATTGCTGGGTTGATAGTATTGGAAGGATTGAAG ATTTTATCAGGAAAAATAGACCAGTGCAGAACAATTTTTTTGAATAAACAACCAAACCCA AGAAAGAAGCTTCTTGTGCCTTGTGCACTGGATCCTCCCAACCCCAATTGTTATGTATGT GCCAGCAAGCCAGAGGTGACTGTGCGGCTGAATGTCCATAAAGTGACTGTTCTCACCTTA CAAGACAAGATAGTGAAAGAAAAATTTGCTATGGTAGCACCAGATGTCCAAATTGAAGAT GGGAAAGGAACAATCCTAATATCTTCCGAAGAGGGAGAGACGGAAGCTAATAATCACAAG AAGTTGTCAGAATTTGGAATTAGAAATGGCAGCCGGCTTCAAGCAGATGACTTCCTCCAG GACTATACTTTATTGATCAACATCCTTCATAGTGAAGACCTAGGAAAGGACGTTGAATTT GAAGTTGTTGGTGATGCCCCGGAAAAAGTGGGGCCCAAACAAGCTGAAGATGCTGCCAAA AGCATAACCAATGGCAGTGATGATGGAGCTCAGCCCTCCACCTCCACAGCTCAAGAGCAA GATGACGTTCTCATAGTTGATTCGGATGAAGAAGATTCTTCAAATAATGCCGACGTCAGT GAAGAAGAGAGAAGCCGCAAGAGGAAATTAGATGAGAAAGAGAATCTCAGTGCAAAGAGG TCACGTATAGAACAGAAGGAAGAGCTTGATGATGTCATAGCATTAGATTGAACAGAAATG CCTCTAAACAGAACCCTCTTACTATTTAGTTTATCTGGGCAGAACCAGATTGTTATGTCC TTTGTTCCAAAGGGAAAAAATTGACAGCAGTGACTTGAAAATGATTCTGCTCCCTTTGAA AGCATTCATTTTGCTAGAACTGTTAGACACATTGCAGTATGCTGTATTGAAAGTAGGAAT ATAGTTTTAAAAACCCTTTGAACAAAGTGTGTGCATAACCAGTCATGAGATAAAACAACA CAATGCATGTTGCCTTTTTAATGTAAATACCCTTAGGTATCATTAATAGTTTCAAAATAT TGTGGTTTAGTAAAGTTGATACCTGGTTATAAATATTATGCCTTTATTTTTGGCTAGAAG AAGAATTATTTTTAGCCTAGATCTAACCATTTTCATACTCTTAACTGATTGAAACAGATT CAAAGAAGTATCGAGTGCTATGCATTGAAACTTGTTTTTAAATGTTAGATGGCACTATGT ATATTAATGTAAAACAATGTTAATTTACTCAAGTTTTCAGTTTGTACCGCCTGGTATGTC TGTGTAAGAAGCCAATTTTTGTGTATTGTTACAGTTTCAGGTTATTTATATTCGATGTTT TGTAAAACTCAAATAACGACTATACTTATGGACCAAATAAATGGCATCTGCATTCTTGTT AAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_005499 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005499.2, NP_005490.1 |
| RefSeq Size | 2682 bp |
| RefSeq ORF | 1923 bp |
| Locus ID | 10054 |
| UniProt ID | Q9UBT2 |
| Domains | UBACT, ThiF |
| Protein Pathways | Ubiquitin mediated proteolysis |
| Gene Summary | Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme
,null,
Cell chemical biology
,PubMed ID 30581133
[UBA2]
|
|
Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure
,Kho, C;Lee, A;Jeong, D;Oh, JG;Gorski, PA;Fish, K;Sanchez, R;DeVita, RJ;Christensen, G;Dahl, R;Hajjar, RJ;,
Nat Commun
,PubMed ID 26068603
[UBA2]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201288 | UBA2 (Myc-DDK-tagged)-Human ubiquitin-like modifier activating enzyme 2 (UBA2) |
CNY 3,990.00 |
|
| RC201288L1 | Lenti ORF clone of Human ubiquitin-like modifier activating enzyme 2 (UBA2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201288L2 | Lenti ORF clone of Human ubiquitin-like modifier activating enzyme 2 (UBA2), mGFP tagged |
CNY 5,890.00 |
|
| RC201288L3 | Lenti ORF clone of Human ubiquitin-like modifier activating enzyme 2 (UBA2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201288L4 | Lenti ORF clone of Human ubiquitin-like modifier activating enzyme 2 (UBA2), mGFP tagged |
CNY 5,890.00 |
|
| RG201288 | UBA2 (tGFP-tagged) - Human ubiquitin-like modifier activating enzyme 2 (UBA2) |
CNY 4,370.00 |
