United States
Germany
Japan
United Kingdom
China
MACC1 (NM_182762) Human Untagged Clone
CAT＃: SC307508
MACC1 (untagged)-Human metastasis associated in colon cancer 1 (MACC1)
CNY 9,368.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 7A5; SH3BP4L |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_182762 edited
GCTTGGGCTCACTTCCACAAATGTGGAAAAATGCTAATCACTGAAAGAAAACATTTTCGG TCAGGAAGAATTGCACAAAGTATGTCTGAAGCAAATTTGATTGACATGGAAGCTGGAAAA CTCTCAAAAAGTTGCAATATTACAGAATGCCAGGACCCAGACTTGCTTCACAATTGGCCG GATGCTTTCACCCTTCGTGGTAATAATGCTTCCAAAGTTGCAAATCCATTCTGGAATCAA CTGTCTGCTTCTAACCCATTTTTGGATGACATAACTCAACTAAGAAATAACAGGAAGAGA AATAATATTTCCATCTTAAAGGAAGATCCTTTTCTTTTCTGTAGAGAAATAGAAAATGGA AATTCTTTTGATTCCTCCGGTGATGAACTTGATGTGCATCAGTTACTTAGGCAGACTTCC TCAAGAAATTCTGGAAGATCTAAAAGTGTTTCAGAACTTCTGGACATTTTAGACGACACA GCACATGCCCATCAGAGTATACATAACTCTGACCAGATCCTACTACACGACTTAGAGTGG CTTAAAAATGATCGGGAGGCTTATAAAATGGCTTGGTTAAGTCAACGCCAGCTGGCCCGC TCCTGCCTTGATTTGAATACAATTAGTCAGAGCCCTGGATGGGCCCAGACACAACTTGCG GAGGTCACCATAGCTTGCAAAGTAAACCATCAAGGAGGGTCAGTACAATTACCTGAATCA GACATCACTGTTCATGTGCCCCAAGGTCATGTGGCTGTGGGAGAATTCCAAGAGGTGTCT CTAAGGGCTTTCCTTGATCCGCCACACATGCTTAACCATGATCTTTCGTGCACTGTGAGC CCGTTGTTGGAAATCATGTTAGGCAACCTCAATACAATGGAAGCCCTTTTGCTGGAGATG AAAATTGGGGCTGAAGTAAGAAAGGATCCTTTCAGCCAAGTCATGACAGAAATGGTGTGT TTACACAGCTTGGGTAAAGAAGGCCCTTTTAAAGTTTTAAGCAACTGCTACATTTATAAA GACACCATCCAAGTCAAGCTAATCGACTTGAGTCAGGTAATGTATCTAGTGGTTGCTGCA CAAGCTAAAGCTCTTCCGTCACCAGCTGCCACCATTTGGGATTATATCCACAAAACCACC TCAATTGGAATTTATGGACCCAAATATATCCATCCCAGTTTTACTGTTGTTTTAACAGTT TGTGGACACAATTATATGCCAGGACAGCTTACAATTTCTGATATTAAGAAGGGTGGAAAA AACATATCTCCAGTTGTGTTTCAGCTCTGGGGGAAGCAGTCATTTTTACTTGACAAGCCA CAAGATTTAAGTATTTCTATTTTTTCCTGTGATCCTGATTTTGAAGTAAAGACAGAAGGA GAAAGGAAAGAAATTAAACAAAAGCAGTTGGAAGCAGGTGAAGTAGTTCATCAACAATTT TTATTTTCTTTAGTTGAGCACAGAGAGATGCACTTGTTTGATTTTTGTGTTCAAGTGGAG CCTCCCAATGGTGAACCAGTTGCACAGTTCTCTATCACTACTCCTGATCCAACCCCAAAC CTAAAAAGACTCTCGAATCTGCCAGGCTATTTGCAGAAGAAGGAGGAAATCAAGTCTGCT CCTTTATCACCAAAAATTCTTGTTAAATATCCTACATTTCAAGATAAAACATTGAACTTT AGCAACTATGGGGTAACCCTGAAGGCAGTGCTAAGACAAAGCAAGATTGATTACTTCCTT GAATATTTCAAAGGGGACACAATAGCTCTCCTCGGGGAAGGTAAGGTAAAAGCTATTGGT CAGTCCAAAGTGAAAGAATGGTATGTAGGAGTCCTCAGAGGTAAGATTGGACTTGTACAC TGCAAAAATGTCAAGGTGATTTCAAAGGAGCAAGTAATGTTTATGTCAGATAGTGTCTTT ACAACCAGAAATCTTCTTGAACAGATTGTCCTGCCTTTAAAAAAATTGACTTATATCTAC TCAGTTGTATTAACCTTGGTGTCAGAAAAAGTTTATGATTGGAAAGTTTTAGCTGATGTC CTGGGTTACTCACATCTGTCCCTGGAAGATTTTGATCAAATTCAAGCAGACAAAGAATCA GAGAAAGTTTCTTATGTTATAAAGAAGTTAAAGGAAGATTGCCACACAGAGAGAAATACA AGGAAGTTTCTGTATGAACTTATTGTGGCTCTTCTGAAAATGGATTGCCAAGAGTTAGTC GCACGTCTCATCCAAGAAGCTGCTGTTCTGACTTCAGCTGTCAAGCTTGGAAAAGGCTGG AGGGAACTAGCTGAAAAGTTAGTACGACTCACAAAGCAACAAATGGAGGCATATGAAATT CCTCATCGAGGAAACACTGGAGATGTTGCTGTTGAGATGATGTGGAAACCTGCCTATGAT TTTCTGTATACCTGGAGTGCTCACTATGGAAATAACTACAGAGATGTGTTACAAGACCTT CAGTCAGCTTTGGACAGAATGAAAAACCCTGTGACTAAACACTGGAGAGAATTAACTGGA GTTTTAATACTAGTAAATTCTTTGGAGGTTTTGAGAGTAACTGCATTCTCCACTTCTGAG GAAGTATAGAAACAAAGCGTGTGTTTTTGATGGGAGGG |
| Restriction Sites | Please inquire |
| ACCN | NM_182762 |
| Insert Size | 2600 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to contain 6 SNPs compared with NM_182762.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_182762.2, NP_877439.2 |
| RefSeq Size | 3188 bp |
| RefSeq ORF | 2559 bp |
| Locus ID | 346389 |
| UniProt ID | Q6ZN28 |
| Gene Summary | MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression
,Kuo, I;Wu, CC;Chang, JM;Huang, YL;,
International Journal of Cancer Dec 2013.
[MACC1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224774 | MACC1 (Myc-DDK-tagged)-Human metastasis associated in colon cancer 1 (MACC1) |
CNY 9,360.00 |
|
| RC224774L1 | Lenti ORF clone of Human metastasis associated in colon cancer 1 (MACC1), Myc-DDK-tagged |
CNY 11,760.00 |
|
| RC224774L2 | Lenti ORF clone of Human metastasis associated in colon cancer 1 (MACC1), mGFP tagged |
CNY 11,760.00 |
|
| RC224774L3 | Lenti ORF clone of Human metastasis associated in colon cancer 1 (MACC1), Myc-DDK-tagged |
CNY 11,760.00 |
|
| RC224774L4 | Lenti ORF clone of Human metastasis associated in colon cancer 1 (MACC1), mGFP tagged |
CNY 11,760.00 |
|
| RG224774 | MACC1 (tGFP-tagged) - Human metastasis associated in colon cancer 1 (MACC1) |
CNY 10,960.00 |
