TLR10 (NM_030956) Human Untagged Clone
CAT＃: SC125241
TLR10 (untagged)-Human toll-like receptor 10 (TLR10), transcript variant 1
CNY 5944.00
CNY 7220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD290 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125241 sequence for NM_030956 edited (data generated by NextGen Sequencing)
ATGAGACTCATCAGAAACATTTACATATTTTGTAGTATTGTTATGACAGCAGAGGGTGAT GCTCCAGAGCTGCCAGAAGAAAGGGAACTGATGACCAACTGCTCCAACATGTCTCTAAGA AAGGTTCCCGCAGACTTGACCCCAGCCACAACGACACTGGATTTATCCTATAACCTCCTT TTTCAACTCCAGAGTTCAGATTTTCATTCTGTCTCCAAACTGAGAGTTTTGATTCTATGC CATAACAGAATTCAACAGCTGGATCTCAAAACCTTTGAATTCAACAAGGAGTTAAGATAT TTAGATTTGTCTAATAACAGACTGAAGAGTGTAACTTGGTATTTACTGGCAGGTCTCAGG TATTTAGATCTTTCTTTTAATGACTTTGACACCATGCCTATCTGTGAGGAAGCTGGCAAC ATGTCACACCTGGAAATCCTAGGTTTGAGTGGGGCAAAAATACAAAAATCAGATTTCCAG AAAATTGCTCATCTGCATCTAAATACTGTCTTCTTAGGATTCAGAACTCTTCCTCATTAT GAAGAAGGTAGCCTGCCCATCTTAAACACAACAAAACTGCACATTGTTTTACCAATGGAC ACAAATTTCTGGGTTCTTTTGCGTGATGGAATCAAGACTTCAAAAATATTAGAAATGACA AATATAGATGGCAAAAGCCAATTTGTAAGTTATGAAATGCAACGAAATCTTAGTTTAGAA CATGCTAAGACATCGGTTCTATTGCTTAATAAAGTTGATTTACTCTGGGACGACCTTTTC CTTATCTTACAATTTGTTTGGCATACATCAGTGGAACACTTTCAGATCCGAAATGTGACT TTTGGTGGTAAGGCTTATCTTGACCACAATTCATTTGACTACTCAAATACTGTAATGAGA ACTATAAAATTGGAGCATGTACATTTCAGAGTGTTTTACATTCAACAGGATAAAATCTAT TTGCTTTTGACCAAAATGGACATAGAAAACCTGACAATATCAAATGCACAAATGCCACAC ATGCTTTTCCCTAATTATCCTACGAAATTCCAATATTTAAATTTTGCCAATAATATCTTA ACAGACGAGTTGTTTAAAAGAACTCTCCAACTGCCTCACTTGAAAACTCTCATTTTGAAT GGCAATAAACTGGAGACACTTTCTTTAGTAAGTTGCTTTGCTAACAACACACCCTTGGAA CACTTGGATCTGAGTCAAAATCTATTACAACATAAAAATGATGAAAATTGCTCATGGCCA GAAACTGTGGTCAATATGAATCTGTCATACAATAAATTGTCTGATTCTGTCTTCAGGTGC TTGCCCAAAAGTATTCAAATACTTGACCTAAATAATAACCAAATCCAAACTGTACCTAAA GAGACTATTCATCTGATGGCCTTACGAGAACTAAATATTGCATTTAATTTTCTAACTGAT CTCCCTGGATGCAGTCATTTCAGTAGACTTTCAGTTCTGAACATTGAAATGAACTTCATT CTCAGCCCATCTCTGGATTTTGTTCAGAGCTGCCAGGAAGTTAAAACTCTAAATGCGGGA AGAAATCCATTCCGGTGTACCTGTGAATTAAAAAATTTCATTCAGCTTGAAACATATTCA GAGGTCATGATGGTTGGATGGTCAGATTCATACACCTGTGAATACCCTTTAAACCTAAGG GGAACTAGGTTAAAAGACGTTCATCTCCACGAATTATCTTGCAACACAGCTCTGTTGATT GTCACCATTGTGGTTATTATGCTAGTTCTGGGGTTGGCTGTGGCCTTCTGCTGTCTCCAC TTTGATCTGCCCTGGTATCTCAGGATGCTAGGTCAATGCACACAAACATGGCACAGGGTT AGGAAAACAACCCAAGAACAACTCAAGAGAAATGTCCGATTCCACGCATTTATTTCATAC AGTGAACATGATTCTCTGTGGGTGAAGAATGAATTGATCCCCAATCTAGAGAAGGAAGAT GGTTCTATCTTGATTTGCCTTTATGAAAGCTACTTTGACCCTGGCAAAAGCATTAGTGAA AATATTGTAAGCTTCATTGAGAAAAGCTATAAGTCCATCTTTGTTTTGTCTCCCAACTTT GTCCAGAATGAGTGGTGCCATTATGAATTCTACTTTGCCCACCACAATCTCTTCCATGAA AATTCTGATCACATAATTCTTATCTTACTGGAACCCATTCCATTCTATTGCATTCCCACC AGGTATCATAAACTGAAAGCTCTCCTGGAAAAAAAAGCATACTTGGAATGGCCCAAGGAT AGGCGTAAATGTGGGCTTTTCTGGGCAAACCTTCGAGCTGCTGTTAATGTTAATGTATTA GCCACCAGAGAAATGTATGAACTGCAGACATTCACAGAGTTAAATGAAGAGTCTCGAGGT TCTACAATCTCTCTGATGAGAACAGACTGTCTATAA Clone variation with respect to NM_030956.3 721 a=>c;1032 g=>t;1105 a=>c;2172 t=>c;2323 a=>g;2427 t=>c >OriGene 5' read for NM_030956 unedited
AGGGAAGTTGNNCNATTGGTAGCCTTTTGAAAACGCCTCACTATAGGGCGGCCGCGAATT NNNNCGAGAACGAATCATCCACGCACCTGCAGCTCTGCTGAGAGAGTGCAAGCCGTGGGG GTTTTGAGCTCATCTTCATCATTCATATGAGGAAATAAGTGGTAGAATCCTTGGAAATAC AATGAGACTCATCAGAAACATTTACATATTTTGTAGTATTGTTATGACAGCAGAGGGTGA TGCTCCAGAGCTGCCAGAAGAAAGGGAACTGATGACCAACTGCTCCAACATGTCTCTAAG AAAGGTTCCCGCAGACTTGACCCCAGCCACAACGACACTGGATTTATCCTATAACCTCCT TTTTCAACTCCAGAGTTCAGATTTTCATTCTGTCTCCAAACTGAGAGTTTTGATTCTATG CCATAACAGAATTCAACAGCTGGATCTCAAAACCTTTGAATTCAACAAGGAGTTAAGATA TTTAGATTTGTCTAATAACAGACTGAAGAGTGTAACTTGGTATTTACTGGCAGGTCTCAG GTATTTAGATCTTTCTTTTAATGACTTTGACACCATGCCTATCTGTGAGGAAGCTGGCAA CATGTCACACCTGGAAATCCTAGGTTTGAGTGGGGCAAAAATACAAAAATCAGATTTCCA GAAAATTGCTCATCTGCATCTAAATACTGTCTTCTTAGGATTCAGAACTCTTCCTCATTA TGAAGAAGGTAGCCTGGCCATCTTANACACAACAAAACTGCACATTGGGTTTACCATGGA CACAAATTTCTGGGGTCTTTNGCGTGATGGAATCAA >OriGene 3' read for NM_030956 unedited
CAGCCAGGAGAGGCACTGNNAAANCNTNAAGGGATGCCACCCGGGATCTGTTCAAGAAAC AGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTGAGAT GGAGTCTCGCTCTGTCACCAGGCTGGAGTGCANTNNCTCNNTCTCAACTCACTGCAACTG CCACCTCCCAAGTTCAAGCGATTCTCCTGCCTCAACCGTCCAAGTAGCTGGGACTACAGG CGAGCACCGTCACTCCCCGCTAACTCTTGGATTTTTAGTAAAAACAAGGTTACACCATGC TGGCCAGGATGGTATACATCTCTTGACCTCAAGGTTAACCCCCCTTGGCCTCCAACAGTG TTGGGATTACAAAATTGAGCCACTGCACCTGGACACACCTTTCATGATAATAAACAATCA TGGGATGAACACCTTCTTCCATAAGCCCTAATAAACCTAGGAAGGTGTTTCTATTTGATA CATTCTTAAAAATCCTTCTATGAACTGATATGAACGGAATAACCCCTTTCAATTATAATA AATATGTGTCAAATTGGCATAATAAACGTTGTATCAAAGAACATCCCAACTAGCATTGTG AGTCCCATCTTTCCAAAGGCTGGGGGCATTTTTAAACAGACTGGTCCTATCTAACATCAT GAAAAACTACAGAATGTTTATTATCATTGTGAAATCTGGATACAATAAATATTCTGCTGT CTAAACTAACTATAACAGACACTCCAAGTTTGCCAAAAGACCAATAACCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_030956 |
| Insert Size | 3600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_030956.2, NP_112218.2 |
| RefSeq Size | 3594 bp |
| RefSeq ORF | 2436 bp |
| Locus ID | 81793 |
| UniProt ID | Q9BXR5 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010] Transcript Variant: This variant (1) represents the longest transcript. Variants 1-4 encode the same protein (isoform a). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation
,H D Park, Y Lee, Y K Oh, J G Jung, Y W Park, K Myung, K-H Kim, S S Koh, D-S Lim,
Oncogene (30 August 2010) doi:10.1038/onc.2010.401 Original Article
[TLR10]
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Other Versions
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| RC216050 | TLR10 (Myc-DDK-tagged)-Human toll-like receptor 10 (TLR10), transcript variant 1 |
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| RC216050L1 | Lenti ORF clone of Human toll-like receptor 10 (TLR10), transcript variant 1, Myc-DDK-tagged |
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| RC216050L2 | Lenti ORF clone of Human toll-like receptor 10 (TLR10), transcript variant 1, mGFP tagged |
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| RC216050L3 | Lenti ORF clone of Human toll-like receptor 10 (TLR10), transcript variant 1, Myc-DDK-tagged |
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| RC216050L4 | Lenti ORF clone of Human toll-like receptor 10 (TLR10), transcript variant 1, mGFP tagged |
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| RG216050 | TLR10 (tGFP-tagged) - Human toll-like receptor 10 (TLR10), transcript variant 1 |
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