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KCNJ5 (NM_000890) Human Untagged Clone
CAT＃: SC119590
KCNJ5 (untagged)-Human potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5)
CNY 2,950.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CIR; GIRK4; KATP1; KIR3.4; LQT13 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000890 edited
GAATTCGGCACGAGGGAGAGGTTCCAGCTACAGCTCCTCCGTGGGGTCATGGCAGGGGCTGGGGAGTCCC CTCAAAAGCCCTGAGCCCCCCTGCACCGCCGCTAAGGGACACCCCAGAAGTTAGCATCAGTGGGACTCGG AAGCTCCGATCTCAACAACATCCCAGCTATGGCTGGCGATTCTAGGAATGCCATGAACCAGGACATGGAG ATTGGAGTCACTCCCTGGGACCCCAAGAAGATTCCAAAACAGGCCCGCGATTATGTCCCCATTGCCACAG ACCGTACGCGCCTGCTGGCCGAGGGCAAGAAGCCACGCCAGCGCTACATGGAGAAGAGCGGCAAGTGCAA TGTGCACCACGGCAACGTCCAGGAGACCTACCGGTACCTGAGTGACCTCTTCACCACCCTGGTGGACCTC AAGTGGCGCTTCAACTTGCTCGTCTTCACCATGGTTTACACTGTCACCTGGCTGTTCTTCGGCTTCATTT GGTGGCTCATTGCTTATATCCGGGGTGACCTGGACCATGTTGGCGACCAAGAGTGGATTCCTTGTGTTGA AAACCTCAGTGGCTTCGTGTCCGCTTTCCTGTTCTCCATTGAGACCGAAACAACCATTGGGTATGGCTTC CGAGTCATCACAGAGAAGTGTCCAGAGGGGATTATACTCCTCTTGGTCCAGGCCATCCTGGGCTCCATCG TCAATGCCTTCATGGTGGGGTGCATGTTTGTCAAGATCAGCCAGCCCAAGAAGAGAGCGGAGACCCTCAT GTTTTCCAACAACGCAGTCATCTCCATGCGGGACGAGAAGCTGTGCCTCATGTTCCGGGTGGGCGACCTC CGCAACTCCCACATCGTGGAGGCCTCCATCCGGGCCAAGCTCATCAAGTCCCGGCAGACCAAAGAGGGGG AGTTCATCCCCCTGAACCAGACAGACATCAACGTGGGCTTTGACACGGGCGACGACCGCCTCTTCCTGGT GTCTCCTCTGATCATCTCCCATGAGATCAACCAGAAGAGCCCTTTCTGGGAGATGTCTCAGGCTCAGCTG CATCAGGAAGAGTTTGAAGTTGTGGTCATTCTAGAAGGGATGGTGGAAGCCACAGGCATGACCTGCCAAG CCCGGAGCTCCTACATGGATACAGAGGTGCTCTGGGGCCACCGATTCACACCAGTCCTCACCTTGGAAAA GGGCTTCTATGAGGTGGACTACAACACCTTCCATGATACCTATGAGACCAACACACCCAGCTGCTGTGCC AAGGAGCTGGCAGAAATGAAGAGGGAAGGCCGGCTCCTCCAGTACCTCCCCAGCCCCCCACTGCTGGGGG GCTGTGCTGAGGCAGGGCTGGATGCAGAGGCTGAGCAGAATGAAGAAGATGAGCCCAAGGGGCTGGGTGG GTCCAGGGAGGCCAGGGGCTCGGTGTGAGGGGTGCAGCCTCCCTAAGACCTCCTGTCACTGGCTTCAGTG AACACAGACACTGCAGAGCCTGGGAGCAGGGGAGGGGAATAGTTGAGTGTGCTGTTTGGGGGCTCAGGAG CCATCAAGGCTGTGGGGAGGAACCATAAACCCAGCCCTCACAGCTCCCAGCACAGGGCCTCCCTGAGCCA GTGGCATCCTGCCTGGGCCCCCCATGGCAGTGCTGCCTCTTGTAGGTGCTGGCTAAGGGCCAGGCCAGGA TGAGTTTCCCCATGGTGAATGTTACCGGATGGCATCTGTTCTCTCCATGCCCTGGGTCACTTCCTTTTTT GGGTCTCACAGACCCCTCCAGGGGCTGACACCTAGAGAGAACCATCACCTTGTCCCTCATTCCTTCCACC CTGAGGCTTGCTGTGGACTCAGAGAGGAGACTTACCTGATGAGAGCTCAAACCTCTAGTCTGGGATGAGC TCACAGAGCCCTCATGAGTTAAGATCCATCCATATCACATAGGCAATTCCTTTTAAATCAGATACCAACG ACCCATTACTGAGAGGTACAGAGCGTACAGCCCTTGGTGTTCTCTGCTGTTATCTGCCAAATGTGTGTGT TTTTCCTCTGCTGTGTTCTGTGTGTCCAGTGTAGCCTATTGGAGAATCGGTCTCATTAGAGTGACTCTTA GAAGGTGGCCTGGGACTAGACAGCCCCTCTGAGCACATGCATAGTGGCATCAGCAGCTTCCTGGCCTACT CCCAATCACACTGTGCCCTGCACCTCCCACCAAGGGGGAACCCCAGCAGCTGGGGCTTTTCGAGTGCTTT TTGGCCCAAGAATCTCAGAGTGCTTCTAATCATCACAGTAGTTTTTGTGTTTTGTTTTGTTTTGTTTTGT TTTGTTTTGTTTTGTTTTGTTTTTTTCACAATCTCAGCCAGCCTGCGGTGTGACCTGGGGAGAAAGTTGA GTGTCAGGGGACATGATGAGCCAGTTGGCCCTGAAACAGGAATGGGGCAAAGAGAAAGGAGAGCCAGGAG CATTTAAAAATCAGCATCTGGGCCAGGCAAGATGGCTCACGCCTGTGATCCCAGCATTTTGGGAGGCCGA GGCGGGTGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTGA AAATACAAAAAATTAGCCAGGCATGGTGGCAGGTGCCTGTAGTCCCAGCTACTCGGGAAGCTGAGGCAGA AGAATGGCATGAACCTGGGAGGTGGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACTCCAGCCTGGGC GACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAACTCGAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000890 |
| Insert Size | 1260 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000890.3, NP_000881.3 |
| RefSeq Size | 2912 bp |
| RefSeq ORF | 1260 bp |
| Locus ID | 3762 |
| UniProt ID | P48544 |
| Domains | IRK |
| Protein Families | Druggable Genome, Ion Channels: Potassium, Transmembrane |
| Gene Summary | This gene encodes an integral membrane protein which belongs to one of seven subfamilies of inward-rectifier potassium channel proteins called potassium channel subfamily J. The encoded protein is a subunit of the potassium channel which is homotetrameric. It is controlled by G-proteins and has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Naturally occurring mutations in this gene are associated with aldosterone-producing adenomas. [provided by RefSeq, Aug 2017] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A Novel KCNJ5-insT149 Somatic Mutation Close to, but Outside, the Selectivity Filter Causes Resistant Hypertension by Loss of Selectivity for Potassium
,Kuppusamy, M;Caroccia, B;Stindl, J;Bandulik, S;Lenzini, L;Gioco, F;Fishman, V;Zanotti, G;Gomez-Sanchez, C;Bader, M;Warth, R;Rossi, GP;,
J. Clin. Endocrinol. Metab. July 2014
,PubMed ID 25057880
[KCNJ5]
|
|
A Novel KCNJ5-insT149 Somatic Mutation Close to,but Outside, the Selectivity Filter Causes ResistantHypertension by Loss of Selectivity for Potassium
,Kuppusamy, M;Caroccia, B;Stindl, J;Bandulik, S;,
J Clin Endocrinol Metab
[KCNJ5]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210184 | KCNJ5 (Myc-DDK-tagged)-Human potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5) |
CNY 5,488.00 |
|
| RC210184L1 | Lenti ORF clone of Human potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC210184L2 | Lenti ORF clone of Human potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5), mGFP tagged |
CNY 5,890.00 |
|
| RC210184L3 | Lenti ORF clone of Human potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210184L4 | Lenti ORF clone of Human potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5), mGFP tagged |
CNY 5,890.00 |
|
| RG210184 | KCNJ5 (tGFP-tagged) - Human potassium inwardly-rectifying channel, subfamily J, member 5 (KCNJ5) |
CNY 7,088.00 |
