MAP3K10 (NM_002446) Human Untagged Clone
CAT＃: SC118630
MAP3K10 (untagged)-Human mitogen-activated protein kinase kinase kinase 10 (MAP3K10)
CNY 10488.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MEKK10; MLK2; MST |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_002446 edited
GCGGCCGCGAATTCGGCACGAGGCCTGCCGCCCTCGCCCTCGTCCCCCACCGGCGGACCC CGGCGGGCATTCGAGAGCCGCGCGGCCAGGCCCTCTTAGCCCTCTGCCGTTTGGGGGGCA CGGGTGAACCTGCCGCCCCACTCCCACCCCGCCCCGCCCCGCCCGTACAGCCAAATCGGA AGGGACGAGCCTGCCCTTTGAAAGGGTTTTTTTTCTTGCTCCTGCGGAGGGCGCCCCAGC CATGGCCCTCAGGAGCTCCCTAGACCCCGCAGGGACTGCCCTCCATCCCGGCCGCCGGGG CCCGCCCTCTGCATCCCGCGGGCAGCCTGTGTGAAGCGGCCTCCCGCAGCCCCCGGCCCC TCCCCCATGGAGGAGGAGGAGGGGGCGGTGGCCAAGGAGTGGGGCACGACCCCCGCGGGG CCCGTCTGGACCGCGGTGTTCGACTACGAGGCGGCGGGCGACGAGGAGCTGACCCTGCGG AGGGGCGATCGCGTCCAGGTGCTTTCCCAAGACTGTGCGGTGTCCGGCGACGAGGGCTGG TGGACCGGGCAGCTCCCCAGCGGCCGCGTGGGCGTCTTCCCCAGCAACTACGTGGCCCCC GGCGCCCCCGCTGCACCCGCGGGCCTCCAGCTGCCCCAGGAGATCCCCTTCCACGAGCTG CAGCTAGAGGAGATCATCGGTGTGGGGGGCTTTGGCAAGGTCTATCGGGCCCTGTGGCGT GGCGAGGAGGTGGCAGTCAAGGCCGCCCGGCTGGACCCTGAGAAGGACCCGGCAGTGACA GCGGAGCAGGTGTGCCAGGAAGCCCGGCTCTTTGGAGCCCTGCAGCACCCCAACATAATT GCCCTTAGGGGCGCCTGCCTCAACCCCCCACACCTCTGCCTAGTGATGGAGTATGCCCGG GGTGGTGCACTGAGCAGGGTGCTGGCAGGTCGCCGGGTGCCACCTCACGTGCTGGTCAAC TGGGCTGTGCAGGTGGCCCGGGGCATGAACTACCTACACAATGATGCCCCTGTGCCCATC ATCCACCGGGACCTCAAGTCCATCAACATCCTGATCCTGGAGGCCATCGAGAACCACAAC CTCGCAGACACGGTGCTCAAGATCACGGACTTCGGCCTCGCCCGCGAGTGGCACAAGACC ACCAAGATGAGCGCTGCGGGGACCTACGCCTGGATGGCGCCGGAGGTTATCCGTCTCTCC CTCTTCTCCAAAAGCAGTGATGTCTGGAGCTTCGGGGTGCTGCTGTGGGAGCTGCTGACG GGGGAGGTCCCCTACCGTGAGATCGACGCCTTGGCCGTGGCGTATGGCGTGGCTATGAAT AAGCTGACGCTGCCCATTCCCTCCACGTGCCCCGAGCCCTTTGCCCGCCTCCTGGAGGAA TGCTGGGACCCAGACCCCCACGGGCGGCCAGATTTCGGTAGCATCTTGAAGCGGCTTGAA GTCATCGAACAGTCAGCCCTGTTCCAGATGCCACTGGAGTCCTTCCACTCGCTGCAGGAA GACTGGAAGCTGGAGATTCAGCACATGTTTGATGACCTTCGGACCAAGGAGAAGGAGCTT CGGAGCCGTGAGGAGGAGCTGCTGCGGGCGGCACAGGAGCAGCGCTTCCAGGAGGAGCAG CTGCGGCGGCGGGAGCAGGAGCTGGCAGAACGTGAGATGGACATCGTGGAACGGGAGCTG CACCTGCTCATGTGCCAGCTGAGCCAGGAGAAGCCCCGGGTCCGCAAGCGCAAGGGCAAC TTCAAGCGCAGCCGCCTGCTCAAGCTGCGGGAAGGCGGCAGCCACATCAGCCTGCCCTCT GGCTTTGAGCATAAGATCACAGTCCAGGCCTCTCCAACTCTGGATAAGCGGAAAGGATCC GATGGGGCCAGCCCCCCTGCAAGCCCCAGCATCATCCCCCGGCTGAGGGCCATTCGCCTG ACTCCCGTGGACTGTGGTGGCAGCAGCAGTGGCAGCAGCAGTGGAGGAAGTGGGACATGG AGCCGCGGTGGGCCCCCAAAGAAGGAAGAACTGGTCGGGGGCAAGAAGAAGGGACGAACG TGGGGGCCCAGCTCCACCCTGCAGAAGGAGCGGGTGGGAGGAGAGGAGAGGTGAGGCTGA AGGGGCTGGGGGAAGGAAGCAAACAGTGGTCATCAAGTGCCCCCAACCTGGGCAAGTCCC CCAAACACACACCCATCGCCCCTGGCTTCGCCAGCCTCAATGAGATGGAGGAGTTCGCGG AGGCAGAGGATGGAGGCAGCAGCGTGCCCCCTTCCCCCTACTCGACCCCGTCCTACCTCT CAGTGCCACTGCCTGCCGAGCCCTCCCCGGGGGCGCGGGCGCCGTGGGAGCCGACGCCGT CCGCGCCCCCCGCTCGGTGGGGACACGGCGCCCGGCGGCGCTGCGACCTGGCGCTGCTAG GCTGCGCCACGCTGCTGGGGGCTGTGGGCCTGGGCGCCGACGTGGCCGAGGCGCGCGCGG CCGACGGTGAGGAGCAGCGGCGCTGGCTCGACGGCCTCTTCTTTCCCCGCGCCGGCCGCT TCCCGCGGGGCCTCAGCCCACCCGCGCGTCCCCACGGCCGCCGCGAAGACGTGGGCCCCG GCCTGGGCCTGGCGCCCTCGGCCACCCTCGTGTCGCTGTCGTCCGTGTCCGACTGCAACT CCACGCGTTCACTGCTGCGCTCTGACAGTGACGAGGCCGCACCGGCCGCGCCCTCCCCAC CACCCTCCCCGCCCGCGCCCACACCCACGCCCTCGCCCAGCACCAACCCCCTGGTGGACC TGGAGCTGGAGAGCTTCAAGAAGGACCCCCGCCAGTCGCTCACGCCCACCCACGTCACGG CTGCATGCGCTGTGAGCCGCGGGCACCGGCGGACGCCATCGGATGGGGCGCTGGGGCAGC GGGGGCCGCCCGAGCCCGCGGGCCATGGCCCTGGCCCTCGTGACCTTCTGGACTTCCCCC GCCTGCCCGACCCCCAGGCCCTGTTCCCAGCCCGCCGCCGGCCCCCTGAGTTCCCAGGCC GCCCCACCACCCTGACCTTTGCCCCGAGACCTCGGCCGGCTGCCAGTCGCCCCCGCTTGG ACCCCTGGAAACTGGTCTCCTTCGGCCGGACACTCACCATCTCGCCTCCCAGCAGGCCAG ACACTCCGGAGAGCCCTGGGCCCCCCAGCGTGCAGCCCACACTGCTGGACATGGACATGG AGGGGCAGAACCAAGACAGCACAGTGCCCCTGTGCGGGGCCCACGGCTCCCACTAAGGCC TGCCCACCACCGCCCGCCTGGGCAGCCATGAATGTAGCGCCCCAGGCCCTGCCCCAGCCC GCCATGCCACAAGGTGGGGGAGGCCCTGGGCAGGATGTTCACTCTATTTA >OriGene 5' read for NM_002446 unedited
CCGGTTGCGATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCCTGCCG CCCTCGCCCTCGTCCCCCCCGGCGGACCCCGGCGGGCATTCGAGAGCCGCGCGGCCAGGC CCTCTTAGCCCTCTGCCGTTTGGGGGGCACGGGTGAACCTGCCGCCCCACTCCCACCCCG CCCCGCCCCGCCCGTACAGCCAAATCGGAAGGGACGAGCCTGCCCTTTGAAAGGGTTTTT TTTCTTGCTCCTGCGGAGGGCGCCCCAGCCATGGCCCTCAGGAGCTCCCTAGACCCCGCA GGGACTGCCCTCCATCCCGGCCGCCGGGGCCCGCCCTCTGCATCCCGCGGGCAGCCTGTG TGAAGCGGCCTCCCGCAGCCCCCGGCCCCTCCCCCATGGAGGAGGAGGAGGGGGCGGTGG CCAAGGAGTGGGGCACGACCCCCGCGGGGCCCGTCTGGACCGCGGTGTTCGACTACGAGG CGGCGGGCGACGAGGAGCTGACCCTGCGGAGGGGCGATCGCGTCCAGGTGCTTTCCCAAG ACTGTGCGGTGTCCGGCGACGAGGGCTGGTGGACCGGGCAGCTCCCCAGCGGCCGCGTGG GCGTCTTCCCCAGCAACTACGTGGCCCCCGGCGCCCCCGCTGCACCCGCGGGCCTCCAGC TGCCCCAGGAGATCCCCTTCCACGAGCTGCAGCTAGAGGAGATCATCGGTGTGGGGGGCT TTGGCAAGGTCTATCGGGCCCTGTGGCGTGGCGAGGAGGTGGCAGTCAAGGCCGCCCGGC TGGACCCTGAGAAGGACCCGGCAGTGACAGCGGAGCAGGTGTGCCAGGAAGCCCGGCTCT TTGGAGCCCTGCAGCACCCCCACATAATTGCCCTTAGGGGGCGCCTGCTNNACCNCCACA CCTCTGCCTAGTGT >OriGene 3' read for NM_002446 unedited
GGGGGAAATTCTGTGTACCGCGCCCCTTACTANGATCGATTTTTCTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAGGGGGCAGGGGTTACCTTTAATGCTCCA TTTTGGGCCAAATCCCCCATGATGCCCTGTCCCTGAATATCCCTGCCCACCCTCCCCCCA TTGCAGGGGGGGCAAAGGGTTCCCCCCCCTGGGGTTCAAAGGAATAATTTAAGTGTCCCC CCCCTCCCTCTTTCCCAAAAAAAAAAAGTGAAAATCCTGCCCAGGGCCTCCCCCACCTTT TGGCATGGCGGGTTGGGGCAGGGCCTGGGGCCCTACATTTATGGTTTCCCAAGCGGGCGG TGGTGGGCAGGCCTTATTGGGACCCGTGGGCCCCCCACAGGGGCACTGTGCTGTTTTGGT TTTGCCCCTCCATGTCCATTTCCAACATTGTGGGCTGCACCCTGGGGGGCCCAGGGCTTT CCGGAATGTTTGGCCTGTTGGGAGGCAAAATGGTAATTTTCCGGCCAAAGGAAACCATTT TCCAGGGGTCCAAACGGGGGCAACTGGCACCCGGCCGAAGTTTCGGGGCAAAAGTCAAGG TGGGGGGGCGGCCTGGAAACTCAAGGGGCCCGGGGCGGGTTTGAAACAGGGCCTGGGGGT TGGGCAACCGGGGGAAATCCAAAAGGTCAAAGGGCCAGGGCCATGGCCCGGGGGTTTGGG GGGGCCCCTGTTTCCCAAACGCCCCATTCAAAGGGTTTCCCCGGTCCCCGGGTTTAAAAA AAATTCACCCTTGACTTGTGTGGGCCTTAACCCAATTGGGGGGGGTCCTTTTTTAAACTC TTCACACTCCGGTTCCCCCAGG |
| Restriction Sites | Please inquire |
| ACCN | NM_002446 |
| Insert Size | 3800 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002446.2, NP_002437.2 |
| RefSeq Size | 3428 bp |
| RefSeq ORF | 2865 bp |
| Locus ID | 4294 |
| UniProt ID | Q02779 |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218669 | MAP3K10 (Myc-DDK-tagged)-Human mitogen-activated protein kinase kinase kinase 10 (MAP3K10) |
CNY 10480.00 |
|
| RC218669L1 | Lenti-ORF clone of MAP3K10 (Myc-DDK-tagged)-Human mitogen-activated protein kinase kinase kinase 10 (MAP3K10) |
CNY 12880.00 |
|
| RC218669L2 | Lenti-ORF clone of MAP3K10 (mGFP-tagged)-Human mitogen-activated protein kinase kinase kinase 10 (MAP3K10) |
CNY 9030.00 |
|
| RC218669L3 | Lenti-ORF clone of MAP3K10 (Myc-DDK-tagged)-Human mitogen-activated protein kinase kinase kinase 10 (MAP3K10) |
CNY 9030.00 |
|
| RC218669L4 | Lenti-ORF clone of MAP3K10 (mGFP-tagged)-Human mitogen-activated protein kinase kinase kinase 10 (MAP3K10) |
CNY 12880.00 |
|
| RG218669 | MAP3K10 (tGFP-tagged) - Human mitogen-activated protein kinase kinase kinase 10 (MAP3K10) |
CNY 7890.00 |
|
| SC323447 | MAP3K10 (untagged)-Kinase deficient mutant (K125M) of Human mitogen-activated protein kinase kinase kinase 10 (MAP3K10) |
CNY 10488.00 |
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