PYROXD1 (NM_024854) Human Untagged Clone
CAT＃: SC111958
PYROXD1 (untagged)-Human pyridine nucleotide-disulphide oxidoreductase domain 1 (PYROXD1)
CNY 3728.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MFM8 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111958 sequence for NM_024854 edited (data generated by NextGen Sequencing)
ATGGAGGCAGCGCGCCCTCCCCCGACGGCAGGGAAGTTCGTGGTGGTCGGCGGCGGCATC GCGGGCGTCACTTGTGCGGAGCAGTTGGCTACTCACTTTCCATCGGAAGATATTCTCTTG GTAACAGCTTCTCCTGTTATTAAAGCAGTTACAAATTTCAAGCAGATTTCTAAAATATTG GAAGAATTCGATGTTGAAGAACAATCAAGTACCATGTTAGGAAAACGCTTTCCCAACATT AAGGTTATAGAATCTGGCGTAAAGCAACTGAAGAGTGAAGAACACTGCATTGTAACAGAA GATGGCAATCAGCACGTATATAAGAAACTCTGTCTGTGTGCTGGAGCTAAACCAAAGTTG ATATGTGAAGGAAATCCTTATGTATTAGGAATCCGTGATACAGACAGTGCTCAGGAATTT CAGAAACAGCTTACTAAAGCTAAAAGAATAATGATCATAGGGAACGGTGGTATTGCACTT GAGTTAGTGTATGAAATTGAAGGCTGTGAAGTGATTTGGGCCATTAAAGATAAAGCTATA GGGAATACTTTCTTCGATGCAGGAGCAGCTGAATTCTTGACTTCAAAGCTCATTGCTGAA AAATCAGAGGCTAAAATTGCACATAAAAGAACCAGATATACAACTGAAGGAAGGAAAAAG GAAGCTAGAAGCAAATCTAAAGCAGATAATGTAGGAAGTGCATTGGGACCAGATTGGCAT GAAGGCTTGAATCTTAAAGGAACAAAAGAGTTTTCTCATAAGATTCACCTTGAAACTATG TGTGAAGTAAAGAAAATCTACCTTCAGGATGAGTTTAGAATTTTGAAGAAAAAGTCCTTC ACTTTTCCAAGAGACCATAAGTCAGTTACAGCTGATACAGAGATGTGGCCTGTCTATGTG GAATTGACCAATGAAAAGATATATGGCTGCGATTTCATTGTCAGTGCTACAGGAGTTACA CCAAATGTAGAACCTTTTCTCCATGGTAACAGTTTTGATCTAGGAGAAGATGGTGGCCTG AAAGTGGATGATCATATGCACACATCCCTTCCTGATATCTATGCTGCCGGTGACATCTGT ACTACATCCTGGCAGCTGAGCCCAGTCTGGCAGCAGATGAGGCTGTGGACCCAGGCTAGA CAGATGGGATGGTATGCAGCAAAGTGCATGGCTGCAGCGAGTTCAGGAGACTCTATTGAC ATGGATTTCAGCTTTGAACTGTTTGCTCATGTGACAAAATTTTTTAACTATAAGGTTGTA CTGCTGGGAAAATACAATGCACAGGGCTTAGGTTCAGATCATGAATTAATGCTGAGATGT ACCAAAGGACGAGAATACATCAAAGTCGTCATGCAAAATGGACGAATGATGGGAGCTGTC TTAATTGGTGAAACCGATTTAGAAGAAACATTTGAAAACCTAATCTTAAACCAAATGAAT CTTTCATCATATGGAGAAGATCTGCTAGATCCAAATATTGATATAGAAGATTATTTTGAC TAA Clone variation with respect to NM_024854.3 >OriGene 5' read for NM_024854 unedited
CAGTCAGATTTGTACTCGATCATATGGGCGGCCGCTGAATCGGCACGAGGCCTCGTGCCG AATTCGGCACGAGGCAGTAAACCACTGGGAGTCCGGCAGCATGGAGGCAGCGCGCCCTCC CCCGACGGCAGGGAAGTTCGTGGTGGTCGGCGGCGGCATCGCGGGCGTCACTTGTGCGGA GCAGTTGGCTACTCACTTTCCATCGGAAGAGATTCTCTTGGTAACAGCTTCTCCTGTTAT TAAAGCAGTTACAAATTTCAAGCAGATTTCTAAAATATTGGAAGAATTCGATGTTGAAGA ACAATCAAGTACCATGTTAGGAAAACGCTTTCCCAACATTAAGGTTATAGAATCTGGCGT AAAGCAACTGAAGAGTGAAGAACACTGCATTGTAACAGAAGATGGCAATCAGCACGTATA TAAGAAACTCTGTCTGTGTGCTGGAGCTAAACCAAAGTTGATATGTGAAGGAAATCCTTA TGTATTAGGAATCCGTGATACAGACAGTGCTCAGGAATTTCAGAAACAGCTTACTAAAGC TAAAAGAATAATGATCATAGGGAACGGTGGTATTGCACTTGAGTTAGTGTATGAAATTGA AGGCTGTGAAGTGATTTGGGCCATTAAAGATAAAGCTATAGGGAATACTTTCTTCGATGC AGGAGCAGCTGACATCTTGACTTCAAAGCTCATTGCTGAAAAATCAGAGGCTAAAATTGC ACATAAAAGAACCTGATATACTACTGAAGGCAGGGACAAAGGAAGCTAGTACGCANATCT AAAGCAGATAATGTAGGACGTGCATTTGGACCGCACTGCATGACGGCTTGATCTTACAGA ACTAAAGAGTTCTCATACGATCACTTTGAACTTGTGTGAGTAAAGAGATCTACCTCNNGA TGAGTTAGATTTGAGAGCAGCCTCCT >OriGene 3' read for NM_024854 unedited
NCTTTCTATGNNACCGCGGCCGCATTTCTANGATCGAGTTTTTTTTTTTTTTTTTTGTAG GCTGAATCGTCTCAAACTTGTCATTCTGAACAAGGTGATAAAAAGATGGAGGAAAAAAAT CAGGCAACTTCCAGAAGAAGGCTGCAAACATGCTTCAGCAATCTGGTTCTAAGAATACAG GAGCTAAGAAAAGAAAAATCGATGATGCCTGATATGAATGTTACTAAATTTTCTAATTAA AGATGGTTTATGCATGTATATGCCATTATTTTTGTAGTTAGACAATAGTTTTTAAAAGAA TTTCATAGATATTTTATATGTATGGATCTATATTTTCAGAGCTTATCTCTGAAGATCTAA ACTTTTGAGAATGTTTGAAAATTAGAGATCATGAATTATATAATTTTCCAGTATAAAACA AGGGAAAAATTTTTATGTAAAACCCTTTAAATGTAAAATATTTGAGAATAAGTTCATACA ATCGTCTTAAGTTTTTTATGCCTTTATATACTTAGCTATATTTTTTCTTTTGACATAACT ATCTTTTTGAAAGCAATATTATACTGACAGAGGCTCACTGAGTGATACTTTAAGTTAAAT ATGTAGATCAAGGATGTCCAATCTTTTGGCTTCCCTGAGCCACATTGGAAGAAGAATTGT CTTGGGCCGCACATAAAATATGCTAACACTGATGATAGCTGATGAGCTTAAAAAAAAAAT TGCAAGAAAAATCTCATGTTTTAAGAAAGTTTACAAAAAATGTAAATATTTGAGAAATAG TTCATGTAAATTGTCCTAAGTTTTTTATGCCTTTATATACTTAGCTATATTTNTTTCTTT TGACATAACCCATCTTTTTGAAAGCAATATTATACTGACAGAGGGTCACTGAGTGATACT TTAAGTAAATATGTAGATAGGGATGTCCAATCTTTTGGCTTCCTGAGCCCCATGGNAGAA GAATGTCTTGGCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_024854 |
| Insert Size | 3490 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_024854.2, NP_079130.2 |
| RefSeq Size | 3171 bp |
| RefSeq ORF | 1503 bp |
| Locus ID | 79912 |
| UniProt ID | Q8WU10 |
| Domains | pyr_redox |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a nuclear-cytoplasmic pyridine nucleotide-disulphide reductase (PNDR). PNDRs are flavoproteins that catalyze the pyridine nucleotide-dependent reduction of thiol residues in other proteins. The encoded protein belongs to the class I pyridine nucleotide-disulphide oxidoreductase family but lacks the C-terminal dimerization domain found in other family members and instead has a C-terminal nitrile reductase domain. It localizes to the nucleus and to striated sarcomeric compartments. Naturally occurring mutations in this gene cause early-onset myopathy with internalized nuclei and myofibrillar disorganization. A pseudogene of this gene has been defined on chromosome 11. [provided by RefSeq, Apr 2017] Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204614 | PYROXD1 (Myc-DDK-tagged)-Human pyridine nucleotide-disulphide oxidoreductase domain 1 (PYROXD1) |
CNY 3656.00 |
|
| RC204614L3 | Lenti ORF clone of Human pyridine nucleotide-disulphide oxidoreductase domain 1 (PYROXD1), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC204614L4 | Lenti ORF clone of Human pyridine nucleotide-disulphide oxidoreductase domain 1 (PYROXD1), mGFP tagged |
CNY 5890.00 |
|
| RG204614 | PYROXD1 (tGFP-tagged) - Human pyridine nucleotide-disulphide oxidoreductase domain 1 (PYROXD1) |
CNY 5256.00 |
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