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FUS (NM_004960) Human Tagged Lenti ORF Clone
CAT＃: RC201808L2
- LentiORF®
Lenti ORF clone of Human fused in sarcoma (FUS), transcript variant 1, mGFP tagged
"NM_004960" in other vectors (6)
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CNY 5,890.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | mGFP |
| Synonyms | ALS6; altFUS; ETM4; FUS1; HNRNPP2; POMP75; TLS |
| Vector | pLenti-C-mGFP |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC201808).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_004960 |
| ORF Size | 1578 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004960.2 |
| RefSeq Size | 5119 bp |
| RefSeq ORF | 1581 bp |
| Locus ID | 2521 |
| UniProt ID | P35637 |
| Domains | RRM, zf-RanBP |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| MW | 53.4 kDa |
| Gene Summary | This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients
,Bennett, CL;Dastidar, SG;Ling, SC;Malik, B;Ashe, T;Wadhwa, M;Miller, DB;Lee, C;Mitchell, MB;van Es, MA;Grunseich, C;Chen, Y;Sopher, BL;Greensmith, L;Cleveland, DW;La Spada, AR;,
Acta Neuropathol.
,PubMed ID 29725819
[FUS]
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Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201808 | FUS (Myc-DDK-tagged)-Human fused in sarcoma (FUS), transcript variant 1 |
CNY 3,920.00 |
|
| RC201808L1 | Lenti ORF clone of Human fused in sarcoma (FUS), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201808L3 | Lenti ORF clone of Human fused in sarcoma (FUS), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201808L4 | Lenti ORF clone of Human fused in sarcoma (FUS), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG201808 | FUS (tGFP-tagged) - Human fused in sarcoma (FUS), transcript variant 1 |
CNY 4,370.00 |
|
| SC320263 | FUS (untagged)-Human fused in sarcoma (FUS), transcript variant 1 |
CNY 5,888.00 |
