PYCR1 Mouse Monoclonal Antibody [Clone ID: OTI4F2]

Specifications

Product Data
Clone Name	OTI4F2
Applications	IHC, Simple Western, WB
Recommend Dilution	WB 1:500~2000, IHC 1:500 ; Simple Western 1:20-1:50
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-319 of human PYCR1 (NP_008838) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	33.2 kDa
Gene Name	pyrroline-5-carboxylate reductase 1
Database Link	NP_008838 Entrez Gene 209027 MouseEntrez Gene 287877 RatEntrez Gene 5831 Human UniProt ID P32322
Background	This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Synonyms	ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR
Reference Data
Protein Pathways	Arginine and proline metabolism, Metabolic pathways

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