DDX58 Mouse Monoclonal Antibody [Clone ID: OTI6C1]

Specifications

Product Data
Clone Name	OTI6C1
Applications	IF, IHC, WB
Recommend Dilution	WB 1:4000, IHC 1:150, IF 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human DDX58(NP_055129) produced in HEK293T cell.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	106.4 kDa
Gene Name	DExD/H-box helicase 58
Database Link	NP_055129 Entrez Gene 23586 Human UniProt ID O95786
Background	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. [provided by RefSeq, Jul 2008]
Synonyms	RIG-I; RIGI; RLR-1
Reference Data
Protein Pathways	Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway

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