Hsc70 (HSPA8) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1H3]

Specifications

Product Data
Clone Name	OTI1H3
Applications	IF, IHC, WB
Recommend Dilution	WB 1:1000, IHC 1:150, IF 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human HSPA8(NP_006588) produced in HEK293T cell.
Isotype	IgG3
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	HRP
Storage Condition	Store at -20°C as received.
Predicted Protein Size	70.7 kDa
Gene Name	heat shock protein family A (Hsp70) member 8
Database Link	NP_006588 Entrez Gene 15481 MouseEntrez Gene 24468 RatEntrez Gene 3312 Human UniProt ID P11142
Background	This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Synonyms	HEL-33; HEL-S-72p; HSC54; HSC70; HSC71; HSP71; HSP73; HSPA10; LAP-1; LAP1; NIP71
Reference Data
Protein Families	Stem cell - Pluripotency
Protein Pathways	Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Spliceosome

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