RAP2A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Specificity	Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish Homology: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%; Sheep: 93%; Zebrafish: 79%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	20kDa
Gene Name	RAP2A, member of RAS oncogene family
Database Link	NP_066361 Entrez Gene 5911 Human UniProt ID P10114
Background	RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Synonyms	K-REV; KREV; RAP2; RbBP-30
Reference Data
Protein Families	Druggable Genome

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